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    CG18476 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41404, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG18476provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037931
    Locus tag
    Dmel_CG18476
    See related
    AllianceGenome:FB:FBgn0037931
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17822; Dmel\CG18476
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic brain; embryonic/larval midgut; larval ventral nerve cord; and organism. Orthologous to several human genes including ZNF721 (zinc finger protein 721). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG18476 in Genome Data Viewer
    Location:
    86E15-86E15; 3-51 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11674920..11678116, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7500642..7503838, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Elongator complex protein 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene TBP-associated factor 12 Neighboring gene uncharacterized protein Neighboring gene Heme oxygenase

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG18476-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11674920..11678116 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169419.3NP_731615.1  uncharacterized protein Dmel_CG18476 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731615.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QPR1, Q9VGK1, Q9VGK2
      Related
      FBpp0081919
      Conserved Domains (4) summary
      COG5048
      Location:814886
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:790810
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:684
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:830855
      zf-H2C2_2; Zinc-finger double domain