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    gltR two-component response regulator GltR [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 882907, updated on 18-Sep-2024

    Summary

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    Gene symbol
    gltR
    Gene description
    two-component response regulator GltR
    Locus tag
    PA3192
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3583616..3584344, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene sugar ABC transporter substrate-binding protein Neighboring gene two-component sensor Neighboring gene glucokinase Neighboring gene phosphogluconate dehydratase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1. Sage AE, et al. J Bacteriol, 1996 Oct. PMID 8830708, Free PMC Article
    2. GtrS and GltR form a two-component system: the central role of 2-ketogluconate in the expression of exotoxin A and glucose catabolic enzymes in Pseudomonas aeruginosa. Daddaoua A, et al. Nucleic Acids Res, 2014 Jul. PMID 24920832, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GtrS and GltR form a two-component system that regulates the expression from the promoters Pedd/gap-1, PoprB and Pglk, which control the expression of genes involved in glucose metabolism and transport.
      Title: GtrS and GltR form a two-component system: the central role of 2-ketogluconate in the expression of exotoxin A and glucose catabolic enzymes in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables phosphorelay response regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of D-glucose transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    two-component response regulator GltR
    NP_251882.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3583616..3584344 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251882.1 two-component response regulator GltR [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251882.1

      Status: PROVISIONAL

      Conserved Domains (1) summary
      COG0745
      Location:8 → 234
      OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
    Nucleotide Protein
    Heading Accession and Version

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