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    pctA chemotactic transducer PctA [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881565, updated on 11-Sep-2024

    Summary

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    Gene symbol
    pctA
    Gene description
    chemotactic transducer PctA
    Locus tag
    PA4309
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4835264..4837153)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene chemotactic transducer PctC Neighboring gene hypothetical protein Neighboring gene chemotactic transducer PctB Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Correlation between signal input and output in PctA and PctB amino acid chemoreceptor of Pseudomonas aeruginosa. Reyes-Darias JA, et al. Mol Microbiol, 2015 May. PMID 25641105
    2. Purification, crystallization and preliminary crystallographic analysis of the ligand-binding regions of the PctA and PctB chemoreceptors from Pseudomonas aeruginosa in complex with amino acids. Rico-Jiménez M, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2013 Dec. PMID 24316847, Free PMC Article
    3. Genetic identification of chemotactic transducers for amino acids in Pseudomonas aeruginosa. Taguchi K, et al. Microbiology (Reading), 1997 Oct. PMID 9353923
    4. Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non-protein amino acid gamma-aminobutyrate (GABA). Rico-Jiménez M, et al. Mol Microbiol, 2013 Jun. PMID 23650915
    5. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PctA and PctB possess a double PDC (PhoQ-DcuS-CitA) ligand binding domain - a family of binding domain found in various other amino acid chemoreceptors.
      Title: Correlation between signal input and output in PctA and PctB amino acid chemoreceptor of Pseudomonas aeruginosa.
    2. The ligand spectrum of PctA and PctB is quite different since the recombinant ligand-binding region (LBR) of PctA binds 17 different L-amino acids whereas that of PctB recognizes only five.
      Title: Purification, crystallization and preliminary crystallographic analysis of the ligand-binding regions of the PctA and PctB chemoreceptors from Pseudomonas aeruginosa in complex with amino acids.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables amino acid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to amino acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chemotactic transducer PctA
    NP_252999.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4835264..4837153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252999.1 chemotactic transducer PctA [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252999.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      G3XD24
      Conserved Domains (3) summary
      smart00283
      Location:368 → 628
      MA; Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer)
      cd06225
      Location:301 → 347
      HAMP; Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain
      pfam02743
      Location:36 → 261
      dCache_1; Cache domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G3XD24.1

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