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    nis no individualized sperm [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33337, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nisprovided by FlyBase
    Official Full Name
    no individualized spermprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031347
    Locus tag
    Dmel_CG10869
    See related
    AllianceGenome:FB:FBgn0031347
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10869; Dmel\CG10869
    Summary
    Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in spermatogenic failure 35. Orthologous to human QRICH2 (glutamine rich 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See nis in Genome Data Viewer
    Location:
    22A3-22A3; 2-3 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1584866..1587155, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1584866..1587155, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Odorant receptor 22a Neighboring gene Odorant receptor 22b Neighboring gene hattifattener Neighboring gene RAB3 GTPase activating protein subunit 1 Neighboring gene uncharacterized protein Neighboring gene Rieske iron-sulfur protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Molecular and Genetic Characterization of Second Chromosome Balancers in Drosophila melanogaster. Miller DE, et al. G3 (Bethesda), 2018 Mar 28. PMID 29420191, Free PMC Article
    2. The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes. Katzenberger RJ, et al. PLoS One, 2012. PMID 22984601, Free PMC Article
    3. A survey of ovary-, testis-, and soma-biased gene expression in Drosophila melanogaster adults. Parisi M, et al. Genome Biol, 2004. PMID 15186491, Free PMC Article
    4. Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila. Lamiable O, et al. Proc Natl Acad Sci U S A, 2016 Jan 19. PMID 26739560, Free PMC Article
    5. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    no individualized sperm
    Names
    CG10869-PA
    nis-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      1584866..1587155 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134761.4 → NP_608605.1  no individualized sperm [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608605.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQ22
      Related
      FBpp0077583
      Conserved Domains (1) summary
      pfam16043
      Location:378 → 562
      DUF4795; Domain of unknown function (DUF4795)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQ22 Q9VQ22

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