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    CG8132 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41121, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8132provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037687
    Locus tag
    Dmel_CG8132
    See related
    AllianceGenome:FB:FBgn0037687
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8132
    Summary
    Predicted to enable omega-amidase activity. Predicted to be involved in asparagine metabolic process; glutamine metabolic process; and oxaloacetate metabolic process. Is expressed in organism. Orthologous to human NIT2 (nitrilase family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8132 in Genome Data Viewer
    Location:
    85D15-85D15; 3-48 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9401495..9402618)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5227217..5228340)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein L34b Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene BBSome interacting protein 1 Neighboring gene uncharacterized protein Neighboring gene beta-Tubulin at 85D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An RNAi Screen for Genes Required for Growth of Drosophila Wing Tissue. Rotelli MD, et al. G3 (Bethesda), 2019 Oct 7. PMID 31387856, Free PMC Article
    2. A Genetic Screen Using the Drosophila melanogaster TRiP RNAi Collection To Identify Metabolic Enzymes Required for Eye Development. Pletcher RC, et al. G3 (Bethesda), 2019 Jul 9. PMID 31036678, Free PMC Article
    3. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article
    4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    5. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables omega-amidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in asparagine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glutamine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in oxaloacetate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8132-PA
    NP_649888.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9401495..9402618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141631.3 → NP_649888.1  uncharacterized protein Dmel_CG8132 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649888.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHE4
      Related
      FBpp0081507
      Conserved Domains (1) summary
      cd07572
      Location:9 → 272
      nit; Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHE4 Q9VHE4

    Gene LinkOut

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