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    Sh3bgr SH3 domain binding glutamate-rich protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498066, updated on 2-Nov-2024

    Summary

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    Symbol
    Sh3bgrprovided by RGD
    Full Name
    SH3 domain binding glutamate-rich proteinprovided by RGD
    Primary source
    RGD:1563599
    See related
    EnsemblRapid:ENSRNOG00000028238 AllianceGenome:RGD:1563599
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563599
    Summary
    Predicted to be active in cytoplasm. Orthologous to human SH3BGR (SH3 domain binding glutamate rich protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 2469.7) and Heart (RPKM 1235.5) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sh3bgr in Genome Data Viewer
    Location:
    11q11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (48973033..48997328)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (35503663..35527853)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (36555354..36579537)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene guided entry of tail-anchored proteins factor 1 Neighboring gene lebercilin LCA5 like Neighboring gene Beta-1,3-galactosyltransferase 5 Neighboring gene microRNA 6325

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. Hu YH, et al. BMC Genomics, 2006 Jun 16. PMID 16780588, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SH3 domain-binding glutamic acid-rich protein
    Names
    SH3 domain-binding glutamic acid-rich protein-like
    SH3-binding domain glutamic acid-rich protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127682.1 → NP_001121154.1  SH3 domain-binding glutamic acid-rich protein

      See identical proteins and their annotated locations for NP_001121154.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474083
      UniProtKB/TrEMBL
      A6KPR6, D3ZU20
      Related
      ENSRNOP00000063900.1, ENSRNOT00000064981.5
      Conserved Domains (1) summary
      pfam04908
      Location:1 → 98
      SH3BGR; SH3-binding, glutamic acid-rich protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      48973033..48997328
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006248184.3 → XP_006248246.1  SH3 domain-binding glutamic acid-rich protein isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZ80
      Conserved Domains (1) summary
      pfam04908
      Location:1 → 98
      SH3BGR; SH3-binding, glutamic acid-rich protein

    2. XM_063270698.1 → XP_063126768.1  SH3 domain-binding glutamic acid-rich protein isoform X1

    3. XM_039088575.2 → XP_038944503.1  SH3 domain-binding glutamic acid-rich protein isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZZ80
      Conserved Domains (1) summary
      cd03030
      Location:2 → 77
      GRX_SH3BGR; Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif. ...

    4. XM_039088574.2 → XP_038944502.1  SH3 domain-binding glutamic acid-rich protein isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZZ80
      Related
      ENSRNOP00000084404.1, ENSRNOT00000119421.2
      Conserved Domains (1) summary
      cl00388
      Location:14 → 97
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    5. XM_063270699.1 → XP_063126769.1  SH3 domain-binding glutamic acid-rich protein isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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