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    Rbms1 RNA binding motif, single stranded interacting protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362138, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rbms1provided by RGD
    Official Full Name
    RNA binding motif, single stranded interacting protein 1provided by RGD
    Primary source
    RGD:1307777
    See related
    EnsemblRapid:ENSRNOG00000008482 AllianceGenome:RGD:1307777
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to be involved in DNA replication. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytosol and nucleus. Orthologous to human RBMS1 (RNA binding motif single stranded interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 139.4), Heart (RPKM 104.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rbms1 in Genome Data Viewer
    Location:
    3q21
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (65604475..65829072, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (45195828..45420406, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (46802870..47025178, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene integrin subunit beta 6 Neighboring gene uncharacterized LOC108350379 Neighboring gene uncharacterized LOC134486286 Neighboring gene proteasome 26S subunit, non-ATPase 8, pseudogene 1 Neighboring gene uncharacterized LOC108352564

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables poly(A) binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables poly(U) RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding motif, single-stranded-interacting protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012184.1 → NP_001012184.1  RNA-binding motif, single-stranded-interacting protein 1

      See identical proteins and their annotated locations for NP_001012184.1

      Status: PROVISIONAL

      Source sequence(s)
      BC087094
      UniProtKB/Swiss-Prot
      Q5PQP1
      UniProtKB/TrEMBL
      A0A8L2Q545, A6HLT5
      Related
      ENSRNOP00000095266.1, ENSRNOT00000099437.2
      Conserved Domains (2) summary
      cd12470
      Location:55 → 140
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:141 → 226
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      65604475..65829072 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284115.1 → XP_063140185.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X13

      UniProtKB/TrEMBL
      A0A8I5Y9I4, A0A8I5ZLN8
      Related
      ENSRNOP00000078893.1, ENSRNOT00000114670.2

    2. XM_063284113.1 → XP_063140183.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8I5Y9I4

    3. XM_063284114.1 → XP_063140184.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A8L2Q545

    4. XM_006234237.4 → XP_006234299.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8L2Q545
      Conserved Domains (2) summary
      cd12470
      Location:57 → 142
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:143 → 228
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

    5. XM_063284116.1 → XP_063140186.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X14

      UniProtKB/TrEMBL
      A0A8L2Q545
      Related
      ENSRNOP00000011682.5, ENSRNOT00000011682.8

    6. XM_039105393.2 → XP_038961321.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X3

      UniProtKB/TrEMBL
      A6HLT6
      Conserved Domains (3) summary
      TIGR01645
      Location:83 → 373
      half-pint; poly-U binding splicing factor, half-pint family
      cd12470
      Location:54 → 139
      RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12473
      Location:140 → 224
      RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

    7. XM_006234235.4 → XP_006234297.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8L2Q545
      Related
      ENSRNOP00000077414.2, ENSRNOT00000112740.2
      Conserved Domains (2) summary
      cd12470
      Location:55 → 140
      RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12473
      Location:141 → 225
      RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

    8. XM_006234238.5 → XP_006234300.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A8L2Q545
      Related
      ENSRNOP00000073145.3, ENSRNOT00000087439.3
      Conserved Domains (2) summary
      cd12470
      Location:57 → 142
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:143 → 228
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

    9. XM_006234234.5 → XP_006234296.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8L2Q545
      Conserved Domains (2) summary
      cd12470
      Location:57 → 142
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:143 → 228
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

    10. XM_063284117.1 → XP_063140187.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X15

      UniProtKB/TrEMBL
      A0A8I6AJP2, A0A8L2Q545
      Related
      ENSRNOP00000094484.1, ENSRNOT00000101661.2

    11. XM_039105397.2 → XP_038961325.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X16

      UniProtKB/TrEMBL
      A6HLT8
      Conserved Domains (3) summary
      TIGR01645
      Location:51 → 341
      half-pint; poly-U binding splicing factor, half-pint family
      cd12470
      Location:22 → 107
      RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12473
      Location:108 → 192
      RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

    12. XM_017591893.3 → XP_017447382.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A8L2Q545
      Related
      ENSRNOP00000082356.2, ENSRNOT00000115982.2

    13. XM_006234239.5 → XP_006234301.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X9

      See identical proteins and their annotated locations for XP_006234301.1

      UniProtKB/TrEMBL
      A0A8L2Q545
      Conserved Domains (2) summary
      cd12470
      Location:39 → 124
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:125 → 210
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

    14. XM_006234241.5 → XP_006234303.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X11

      See identical proteins and their annotated locations for XP_006234303.1

      UniProtKB/TrEMBL
      A0A0G2K4R7, A6HLT7
      Conserved Domains (2) summary
      cd12470
      Location:53 → 138
      RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12473
      Location:139 → 223
      RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

    15. XM_006234236.5 → XP_006234298.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A0G2K4R7
      Conserved Domains (2) summary
      cd12470
      Location:53 → 138
      RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12473
      Location:139 → 223
      RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

    16. XM_039105394.2 → XP_038961322.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A0G2K4R7
      Conserved Domains (2) summary
      cd12470
      Location:52 → 137
      RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12473
      Location:138 → 222
      RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

    17. XM_039105398.2 → XP_038961326.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X17

      Conserved Domains (1) summary
      cl17169
      Location:1 → 38
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5PQP1.1 GenPept UniProtKB/Swiss-Prot:Q5PQP1

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