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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001160313.3 → NP_001153785.2 neurofascin isoform 2 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The promoter and 5' UTR for this variant have not been determined. The resulting isoform (2) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and has several differences near the N-terminus, compared to isoform 1. Isoform 2 is also known as NF155, as described by Davis et al. (PMID: 8947556).
- Source sequence(s)
-
JAXUCZ010000013
- UniProtKB/TrEMBL
- A6IC61, D3ZW56
- Conserved Domains (7) summary
-
- cd00063
Location:639 → 729
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam13882
Location:1081 → 1161
- Bravo_FIGEY; Bravo-like intracellular region
- cd00096
Location:365 → 369
- Ig; Ig strand B [structural motif]
- cd05731
Location:263 → 345
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
- cd05845
Location:138 → 228
- IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
- cd05875
Location:35 → 129
- IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
- cl11960
Location:349 → 437
- Ig; Immunoglobulin domain
-
NM_001160314.3 → NP_001153786.1 neurofascin isoform 1 precursor
See identical proteins and their annotated locations for NP_001153786.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). This isoform lacks the third fibronectin type 3 (FNIII) repeat and includes the mucin-like domain. Isoform 1 is also known as NF186, as described by Davis et al. (PMID: 8947556).
- Source sequence(s)
-
JAXUCZ010000013
- UniProtKB/Swiss-Prot
- P97684, P97685, Q91Z60
- UniProtKB/TrEMBL
-
A6IC58
- Related
- ENSRNOP00000057594.4, ENSRNOT00000060871.6
- Conserved Domains (9) summary
-
- cd05731
Location:264 → 334
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
- cd05875
Location:59 → 135
- Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
- smart00408
Location:449 → 508
- IGc2; Immunoglobulin C-2 Type
- smart00410
Location:253 → 333
- IG_like; Immunoglobulin like
- cd00063
Location:628 → 718
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:528 → 609
- I-set; Immunoglobulin I-set domain
- pfam00041
Location:1015 → 1086
- fn3; Fibronectin type III domain
- pfam13882
Location:1132 → 1216
- Bravo_FIGEY; Bravo-like intracellular region
- cl11960
Location:140 → 232
- Ig; Immunoglobulin domain
-
NM_001160315.3 → NP_001153787.1 neurofascin isoform 4 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) represents use of an alternate promoter and 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (4) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and lacks two segments in the N-terminal and central regions, compared to isoform 1.
- Source sequence(s)
-
JAXUCZ010000013
- UniProtKB/TrEMBL
- A0A8I6GIP5, D3ZW56
- Related
- ENSRNOP00000091013.1, ENSRNOT00000110535.2
- Conserved Domains (8) summary
-
- cd05731
Location:258 → 328
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
- cd05875
Location:53 → 129
- Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
- smart00408
Location:443 → 502
- IGc2; Immunoglobulin C-2 Type
- smart00410
Location:247 → 327
- IG_like; Immunoglobulin like
- cd00063
Location:607 → 697
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:522 → 603
- I-set; Immunoglobulin I-set domain
- pfam13882
Location:1049 → 1133
- Bravo_FIGEY; Bravo-like intracellular region
- cl11960
Location:134 → 226
- Ig; Immunoglobulin domain
-
NM_053909.4 → NP_446361.2 neurofascin isoform 3 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (3) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and has several differences in the N-terminal and central regions, compared to isoform 1.
- Source sequence(s)
-
JAXUCZ010000013
- UniProtKB/TrEMBL
- A6IC60, D3ZNW5, D3ZW56
- Conserved Domains (7) summary
-
- cd00063
Location:624 → 714
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam13882
Location:1066 → 1146
- Bravo_FIGEY; Bravo-like intracellular region
- cd00096
Location:365 → 369
- Ig; Ig strand B [structural motif]
- cd05731
Location:263 → 345
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
- cd05845
Location:138 → 228
- IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
- cd05875
Location:35 → 129
- IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
- cl11960
Location:349 → 437
- Ig; Immunoglobulin domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCr8
Genomic
-
NC_086031.1 Reference GRCr8
- Range
-
46549369..46735989 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_063271974.1 → XP_063128044.1 neurofascin isoform X18
- UniProtKB/TrEMBL
-
A0A8I6AN44
-
XM_017598650.3 → XP_017454139.1 neurofascin isoform X14
- UniProtKB/TrEMBL
-
D3ZW56
-
XM_063271966.1 → XP_063128036.1 neurofascin isoform X6
- UniProtKB/TrEMBL
-
A0A8L2QSS8
-
XM_039090280.2 → XP_038946208.1 neurofascin isoform X17
- UniProtKB/TrEMBL
-
A0A8I6AN44
- Conserved Domains (7) summary
-
- cd00063
Location:729 → 819
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam13882
Location:1059 → 1139
- Bravo_FIGEY; Bravo-like intracellular region
- cd00096
Location:470 → 474
- Ig; Ig strand B [structural motif]
- cd05731
Location:368 → 450
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
- cd05845
Location:243 → 333
- IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
- cd05875
Location:140 → 234
- IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
- cl11960
Location:454 → 542
- Ig; Immunoglobulin domain
-
XM_017598649.3 → XP_017454138.1 neurofascin isoform X13
- UniProtKB/TrEMBL
-
A6IC56
-
XM_017598648.3 → XP_017454137.1 neurofascin isoform X12
- UniProtKB/TrEMBL
-
A6IC57
-
XM_063271964.1 → XP_063128034.1 neurofascin isoform X3
- UniProtKB/TrEMBL
-
A0A8L2QSS8
-
XM_063271973.1 → XP_063128043.1 neurofascin isoform X16
- UniProtKB/TrEMBL
-
A0A8I6AN44
- Related
- ENSRNOP00000095471.1, ENSRNOT00000103161.2
-
XM_017598641.3 → XP_017454130.1 neurofascin isoform X5
- UniProtKB/TrEMBL
-
A0A8L2QSS8
- Conserved Domains (8) summary
-
- cd00063
Location:733 → 823
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1226 → 1298
- fn3; Fibronectin type III domain
- pfam13882
Location:1344 → 1424
- Bravo_FIGEY; Bravo-like intracellular region
- cd00096
Location:459 → 463
- Ig; Ig strand B [structural motif]
- cd05731
Location:357 → 439
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
- cd05845
Location:249 → 339
- IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
- cd05875
Location:146 → 240
- IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
- cl11960
Location:443 → 531
- Ig; Immunoglobulin domain
-
XM_063271965.1 → XP_063128035.1 neurofascin isoform X4
- UniProtKB/TrEMBL
-
A0A8L2QSS8
-
XM_063271972.1 → XP_063128042.1 neurofascin isoform X15
- UniProtKB/TrEMBL
-
A0A8I6AN44
-
XM_063271971.1 → XP_063128041.1 neurofascin isoform X9
- UniProtKB/TrEMBL
-
A0A8L2QSS8
- Related
- ENSRNOP00000106961.1, ENSRNOT00000159596.1
-
XM_017598647.3 → XP_017454136.1 neurofascin isoform X11
- UniProtKB/TrEMBL
-
A6IC56
-
XM_039090275.2 → XP_038946203.1 neurofascin isoform X2
- UniProtKB/TrEMBL
-
A6IC59
- Conserved Domains (8) summary
-
- cd00063
Location:750 → 840
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1238 → 1310
- fn3; Fibronectin type III domain
- pfam13882
Location:1356 → 1436
- Bravo_FIGEY; Bravo-like intracellular region
- cd00096
Location:476 → 480
- Ig; Ig strand B [structural motif]
- cd05731
Location:374 → 456
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
- cd05845
Location:249 → 339
- IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
- cd05875
Location:146 → 240
- IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
- cl11960
Location:460 → 548
- Ig; Immunoglobulin domain
-
XM_017598645.3 → XP_017454134.1 neurofascin isoform X10
- UniProtKB/TrEMBL
-
A6IC57
-
XM_063271967.1 → XP_063128037.1 neurofascin isoform X7
- UniProtKB/TrEMBL
-
A0A8I6AN44
-
XM_006249727.5 → XP_006249789.1 neurofascin isoform X1
- UniProtKB/TrEMBL
-
A0A8L2QSS8
- Conserved Domains (9) summary
-
- cd05731
Location:386 → 456
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
- cd05875
Location:164 → 240
- Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
- smart00408
Location:571 → 630
- IGc2; Immunoglobulin C-2 Type
- smart00410
Location:375 → 455
- IG_like; Immunoglobulin like
- cd00063
Location:750 → 840
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:650 → 731
- I-set; Immunoglobulin I-set domain
- pfam00041
Location:1244 → 1315
- fn3; Fibronectin type III domain
- pfam13882
Location:1361 → 1445
- Bravo_FIGEY; Bravo-like intracellular region
- cl11960
Location:245 → 337
- Ig; Immunoglobulin domain
-
XM_063271968.1 → XP_063128038.1 neurofascin isoform X8
- UniProtKB/TrEMBL
-
A6IC59
-
XM_063271969.1 → XP_063128039.1 neurofascin isoform X8
- UniProtKB/TrEMBL
-
A6IC59
-
XM_039090281.2 → XP_038946209.1 neurofascin isoform X19
- UniProtKB/TrEMBL
-
A0A8I6GIE9
- Conserved Domains (6) summary
-
- cd00063
Location:750 → 840
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00096
Location:476 → 480
- Ig; Ig strand B [structural motif]
- cd05731
Location:374 → 456
- Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
- cd05845
Location:249 → 339
- IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
- cd05875
Location:146 → 240
- IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
- cl11960
Location:460 → 548
- Ig; Immunoglobulin domain