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    Tmem208 transmembrane protein 208 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291963, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem208provided by RGD
    Official Full Name
    transmembrane protein 208provided by RGD
    Primary source
    RGD:1560953
    See related
    EnsemblRapid:ENSRNOG00000015974 AllianceGenome:RGD:1560953
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Hspc171; RGD1560953
    Summary
    Predicted to be involved in vacuolar protein processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human TMEM208 (transmembrane protein 208). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 246.6), Kidney (RPKM 224.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem208 in Genome Data Viewer
    Location:
    19q11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (50113494..50116210)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (33203587..33206287)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (37282018..37284718)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene engulfment and cell motility 3 Neighboring gene microRNA 328 Neighboring gene leucine rich repeat containing 29 Neighboring gene formin homology 2 domain containing 1 Neighboring gene solute carrier family 9 member A5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in vacuolar protein processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 208

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106179.1 → NP_001099649.1  transmembrane protein 208

      See identical proteins and their annotated locations for NP_001099649.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473972
      UniProtKB/TrEMBL
      A0A8I6AVP2, A6IYP1, D4A266
      Related
      ENSRNOP00000021722.5, ENSRNOT00000021723.7
      Conserved Domains (1) summary
      pfam05620
      Location:9 → 156
      DUF788; Protein of unknown function (DUF788)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      50113494..50116210
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039097607.2 → XP_038953535.1  transmembrane protein 208 isoform X1

      UniProtKB/TrEMBL
      A6IYP2
      Conserved Domains (1) summary
      pfam05620
      Location:8 → 100
      DUF788; Protein of unknown function (DUF788)

    2. XM_063277912.1 → XP_063133982.1  transmembrane protein 208 isoform X2

      UniProtKB/TrEMBL
      A6IYP3
    Nucleotide Protein Strain
    Heading Accession and Version

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