Srp19 signal recognition particle 19 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Srp19provided by RGD
Official Full Name: signal recognition particle 19provided by RGD
Primary source: RGD:1308437
See related: EnsemblRapid:ENSRNOG00000020204 AllianceGenome:RGD:1308437
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable 7S RNA binding activity. Predicted to contribute to ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Predicted to be located in cytosol; nuclear body; and nucleolus. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Orthologous to human SRP19 (signal recognition particle 19). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 174.7), Brain (RPKM 161.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 18p12

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (26205888..26212171)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (25931734..25937974)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (27114822..27121062)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH140681 (e-PCR)
- UniSTS:222749

RH125924 (e-PCR)
- UniSTS:162641

AI228530 (e-PCR)
- UniSTS:250520

RH137512 (e-PCR)
- UniSTS:219600

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 7S RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables 7S RNA binding	ISO Inferred from Sequence Orthology more info
enables RNA binding	ISO Inferred from Sequence Orthology more info
contributes_to ribosome binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nuclear body	IEA Inferred from Electronic Annotation more info
located_in nuclear body	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
part_of signal recognition particle	ISO Inferred from Sequence Orthology more info
part_of signal recognition particle, endoplasmic reticulum targeting	IBA Inferred from Biological aspect of Ancestor more info
part_of signal recognition particle, endoplasmic reticulum targeting	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: signal recognition particle 19 kDa protein

NP_001099627.1

EC 3.6.5.4

XP_063133291.1

EC 3.6.5.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.