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    Tim9a Tim9a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32294, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tim9aprovided by FlyBase
    Official Full Name
    Tim9aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030480
    Locus tag
    Dmel_CG1660
    See related
    AllianceGenome:FB:FBgn0030480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1660; Dmel\CG1660; Tim9
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in protein insertion into mitochondrial inner membrane. Predicted to be part of TIM22 mitochondrial import inner membrane insertion complex and mitochondrial intermembrane space protein transporter complex. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; gut section; larval muscle cell; and mesoderm. Orthologous to human TIMM9 (translocase of inner mitochondrial membrane 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tim9a in Genome Data Viewer
    Location:
    11F1-11F1; 1-43 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13385210..13385893)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13279243..13279926)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Rbp1-like Neighboring gene Yippee Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adaptive evolution of genes duplicated from the Drosophila pseudoobscura neo-X chromosome. Meisel RP, et al. Mol Biol Evol, 2010 Aug. PMID 20351054, Free PMC Article
    2. RNAi screen in Drosophila cells reveals the involvement of the Tom complex in Chlamydia infection. Derré I, et al. PLoS Pathog, 2007 Oct 26. PMID 17967059, Free PMC Article
    3. Genes Relocated Between Drosophila Chromosome Arms Evolve Under Relaxed Selective Constraints Relative to Non-Relocated Genes. Hart MLI, et al. J Mol Evol, 2018 Jul. PMID 29926120
    4. Ecdysone signaling and transcript signature in Drosophila cells resistant against methoxyfenozide. Mosallanejad H, et al. J Insect Physiol, 2010 Dec. PMID 20816975
    5. A P-insertion screen identifying novel X-linked essential genes in Drosophila. Bourbon HM, et al. Mech Dev, 2002 Jan. PMID 11744370

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables unfolded protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein insertion into mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of TIM22 mitochondrial import inner membrane insertion complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial intermembrane space protein transporter complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Tim9a
    Names
    CG1660-PA
    CG1660-PB
    Tim9a-PA
    Tim9a-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13385210..13385893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132653.2 → NP_572881.1  Tim9a, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572881.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1ECC2, Q9VYD7
      UniProtKB/TrEMBL
      X2JEU5
      Related
      FBpp0073606
      Conserved Domains (1) summary
      pfam02953
      Location:17 → 74
      zf-Tim10_DDP; Tim10/DDP family zinc finger

    2. NM_001298279.1 → NP_001285208.1  Tim9a, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285208.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1ECC2, Q9VYD7
      UniProtKB/TrEMBL
      X2JEU5
      Conserved Domains (1) summary
      pfam02953
      Location:17 → 74
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYD7.1 Q9VYD7
    X2JEU5 X2JEU5

    Gene LinkOut

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