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    ACXD Adenylyl cyclase X D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38284, updated on 9-Dec-2024

    Summary

    Official Symbol
    ACXDprovided by FlyBase
    Official Full Name
    Adenylyl cyclase X Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040507
    Locus tag
    Dmel_CG5712
    See related
    AllianceGenome:FB:FBgn0040507
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AC; CG5712; DACXD; Dmel\CG5712
    Summary
    Predicted to enable adenylate cyclase activity. Involved in olfactory behavior. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; embryonic Malpighian tubule; embryonic/larval midgut; germline cell; and gonad. Orthologous to human ADCY2 (adenylate cyclase 2) and ADCY7 (adenylate cyclase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ACXD in Genome Data Viewer
    Location:
    62D3-62D3; 3-2 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (2237608..2243719)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (2237608..2243719)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Outer segment 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables adenylate cyclase activity  
    enables adenylate cyclase activity PubMed 
    enables phosphorus-oxygen lyase activity  
    Component Evidence Code Pubs
    located_in membrane PubMed 
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    adenylyl cyclase X D
    Names
    ACXD-PA
    ACXD-PB
    CG5712-PA
    CG5712-PB
    NP_001261320.1
    NP_620469.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      2237608..2243719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274391.1 → NP_001261320.1  adenylyl cyclase X D, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261320.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PE08
      Conserved Domains (3) summary
      smart00044
      Location:254 → 476
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      pfam16214
      Location:42 → 284
      AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
      cl11967
      Location:321 → 503
      Nucleotidyl_cyc_III; Class III nucleotidyl cyclases
    2. NM_138984.4 → NP_620469.2  adenylyl cyclase X D, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_620469.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGU9, Q9W038
      Related
      FBpp0072753
      Conserved Domains (3) summary
      smart00044
      Location:254 → 476
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      pfam16214
      Location:42 → 284
      AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
      cl11967
      Location:321 → 503
      Nucleotidyl_cyc_III; Class III nucleotidyl cyclases
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