Daao1 D-amino acid oxidase 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Daao1provided by FlyBase
Official Full Name: D-amino acid oxidase 1provided by FlyBase
Primary source: FLYBASE:FBgn0033543
Locus tag: Dmel_CG12338
See related: AllianceGenome:FB:FBgn0033543
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG12338; daao; DAAO; DAO; DDO; Dmel\CG12338
Summary: Predicted to enable D-amino-acid oxidase activity. Predicted to be involved in D-amino acid catabolic process. Predicted to be located in peroxisome. Predicted to be active in cytoplasm. Is expressed in adult head; embryonic midgut chamber; embryonic proventriculus; embryonic/larval midgut; and organism. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to several human genes including DAO (D-amino acid oxidase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (10729578..10731528, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (6617083..6619033, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables D-amino-acid oxidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables D-amino-acid oxidase activity	IEA Inferred from Electronic Annotation more info
enables D-amino-acid oxidase activity	ISS Inferred from Sequence or Structural Similarity more info
enables FAD binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in D-amino acid catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in D-amino acid catabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in D-amino acid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in peroxisome	ISM Inferred from Sequence Model more info	PubMed
located_in peroxisome	ISS Inferred from Sequence or Structural Similarity more info	PubMed

NP_001286292.1

NP_610603.2

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The following sections contain reference sequences that belong to a specific genome build. Explain