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    Igkv2-112 immunoglobulin kappa variable 2-112 [ Mus musculus (house mouse) ]

    Gene ID: 381776, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Igkv2-112provided by MGI
    Official Full Name
    immunoglobulin kappa variable 2-112provided by MGI
    Primary source
    MGI:MGI:3644894
    See related
    Ensembl:ENSMUSG00000076518 IMGT/GENE-DB:IGKV2-112; AllianceGenome:MGI:3644894
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    hg24; Gm5153; EG381776
    Summary
    Predicted to be involved in immune response. Predicted to be part of immunoglobulin complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Igkv2-112 in Genome Data Viewer
    Location:
    6 C1; 6 31.11 cM
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (68196965..68197689)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (68219981..68220705)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa chain complex Neighboring gene immunoglobulin kappa chain variable 2-113 Neighboring gene immunoglobulin kappa variable 14-111 Neighboring gene cortactin pseudogene Neighboring gene predicted gene, 25436

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Somatic diversification is required to generate the V kappa genes of MOPC 511 and MOPC 167 myeloma proteins. Gershenfeld HK, et al. Proc Natl Acad Sci U S A, 1981 Dec. PMID 6801657, Free PMC Article
    2. kappa Chain variable region from M167, a phosphorylcholine binding myeloma protein. Rudikoff S, et al. Biochemistry, 1978 Jul 11. PMID 99160
    3. Evolution of a multigene family of V kappa germ line genes. Joho R, et al. EMBO J, 1984 Jan. PMID 6546718, Free PMC Article
    4. Somatic mutation of immunoglobulin light-chain variable-region genes. Selsing E, et al. Cell, 1981 Jul. PMID 6791832
    5. Sequences of 12 monoclonal anti-dinitrophenyl spin-label antibodies for NMR studies. Leahy DJ, et al. Proc Natl Acad Sci U S A, 1988 Jun. PMID 3375235, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Other Names

    • Ig kappa V-region 24
    • immunoglobulin kappa chain variable 2-112
    • immunoglobulin light chain variable region

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of immunoglobulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of immunoglobulin complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_005612.1 

      Range
      665001..665725
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      68196965..68197689
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P01626.1 GenPept UniProtKB/Swiss-Prot:P01626
    P01627.1 GenPept UniProtKB/Swiss-Prot:P01627
    P01628.1 GenPept UniProtKB/Swiss-Prot:P01628

    Gene LinkOut

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