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    CG10462 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35260, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10462provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032815
    Locus tag
    Dmel_CG10462
    See related
    AllianceGenome:FB:FBgn0032815
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:SD07008; Dmel\CG10462
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; germline cell; larval muscle cell; and visceral mesoderm derivative. Orthologous to human ZNF236 (zinc finger protein 236). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10462 in Genome Data Viewer
    Location:
    38A2-38A2; 2-54 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19732080..19735980, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19732080..19735980, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Leukocyte-antigen-related-like Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44979 Neighboring gene screw Neighboring gene pseudo Neighboring gene Nuclear factor Y-box B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Maternal RNAs encoding transcription factors for germline-specific gene expression in Drosophila embryos. Yatsu J, et al. Int J Dev Biol, 2008. PMID 18956321
    2. FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal. Berger C, et al. Cell Rep, 2012 Aug 30. PMID 22884370, Free PMC Article
    3. Defining the expression of piRNA and transposable elements in Drosophila ovarian germline stem cells and somatic support cells. Story B, et al. Life Sci Alliance, 2019 Oct. PMID 31619466, Free PMC Article
    4. Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets. Rehwinkel J, et al. RNA, 2005 Oct. PMID 16199763, Free PMC Article
    5. Evidence for tissue-specific Jak/STAT target genes in Drosophila optic lobe development. Wang H, et al. Genetics, 2013 Dec. PMID 24077308, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10462-PA
    CG10462-PB
    CG10462-PC
    CG10462-PD
    CG10462-PE
    CG10462-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19732080..19735980 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259167.2 → NP_001246096.1  uncharacterized protein Dmel_CG10462, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246096.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NEU8, Q8T3K6
      Conserved Domains (3) summary
      sd00017
      Location:638 → 658
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:137 → 157
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:679 → 703
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001273669.1 → NP_001260598.1  uncharacterized protein Dmel_CG10462, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260598.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBE3, Q8T3K6
      Conserved Domains (3) summary
      sd00017
      Location:639 → 659
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:137 → 157
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:680 → 704
      zf-H2C2_2; Zinc-finger double domain

    3. NM_136152.4 → NP_609996.2  uncharacterized protein Dmel_CG10462, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609996.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T3K6, Q9VIS7
      Related
      FBpp0080857
      Conserved Domains (3) summary
      sd00017
      Location:639 → 659
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:137 → 157
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:680 → 704
      zf-H2C2_2; Zinc-finger double domain

    4. NM_001038826.3 → NP_001033915.1  uncharacterized protein Dmel_CG10462, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033915.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDT3, Q8T3K6
      Conserved Domains (3) summary
      sd00017
      Location:603 → 623
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:644 → 668
      zf-H2C2_2; Zinc-finger double domain

    5. NM_001273670.1 → NP_001260599.1  uncharacterized protein Dmel_CG10462, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260599.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PD79, Q8T3K6
      Conserved Domains (3) summary
      sd00017
      Location:602 → 622
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:643 → 667
      zf-H2C2_2; Zinc-finger double domain

    6. NM_001038825.3 → NP_001033914.1  uncharacterized protein Dmel_CG10462, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033914.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDT3, Q8T3K6
      Conserved Domains (3) summary
      sd00017
      Location:603 → 623
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:644 → 668
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NEU8 M9NEU8
    M9PBE3 M9PBE3
    M9PD79 M9PD79
    Q2PDT3 Q2PDT3
    Q5BI61 Q5BI61
    Q8T3K6 Q8T3K6
    Q9VIS7 Q9VIS7

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