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    CG32066 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39206, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG32066provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052066
    Locus tag
    Dmel_CG32066
    See related
    AllianceGenome:FB:FBgn0052066
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6487; CG6491; Dmel\CG32066
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Located in perivitelline space. Is expressed in several structures, including adult brain cell body rind; embryonic/larval midgut primordium; ganglia; head epidermis primordium; and synaptic neuropil domain. Orthologous to human CYRIA (CYFIP related Rac1 interactor A) and CYRIB (CYFIP related Rac1 interactor B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32066 in Genome Data Viewer
    Location:
    67E5-67E6; 3-33 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (10640286..10661013, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (10633386..10654113, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene CTD nuclear envelope phosphatase 1 regulatory subunit 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Acireductone dioxygenase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FB elements can promote exon shuffling: a promoter-less white allele can be reactivated by FB mediated transposition in Drosophila melanogaster. Moschetti R, et al. Mol Genet Genomics, 2004 May. PMID 15060822
    2. Population genetic evidence for cold adaptation in European Drosophila melanogaster populations. Božičević V, et al. Mol Ecol, 2016 Mar. PMID 26558479
    3. Functionally Validating Evolutionary Conserved Risk Genes for Parkinson's Disease in Drosophila melanogaster. Baisgaard AE, et al. Insects, 2023 Feb 9. PMID 36835737, Free PMC Article
    4. Identification and characterization of a juvenile hormone response element and its binding proteins. Li Y, et al. J Biol Chem, 2007 Dec 28. PMID 17956872, Free PMC Article
    5. Identification of genes involved in the biology of atypical teratoid/rhabdoid tumours using Drosophila melanogaster. Jeibmann A, et al. Nat Commun, 2014 Jun 3. PMID 24892285

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in perivitelline space HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32066-PB
    CG32066-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      10640286..10661013 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168416.2 → NP_729619.1  uncharacterized protein Dmel_CG32066, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729619.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K1H0
      Related
      FBpp0076007
      Conserved Domains (1) summary
      pfam07159
      Location:22 → 319
      DUF1394; Protein of unknown function (DUF1394)

    2. NM_168417.2 → NP_729620.1  uncharacterized protein Dmel_CG32066, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729620.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K1H0
      Related
      FBpp0076006
      Conserved Domains (1) summary
      pfam07159
      Location:22 → 319
      DUF1394; Protein of unknown function (DUF1394)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K1H0 Q7K1H0

    Gene LinkOut

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