U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG7542 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39960, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG7542provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036738
    Locus tag
    Dmel_CG7542
    See related
    AllianceGenome:FB:FBgn0036738
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7542; SP71
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in innate immune response and proteolysis. Predicted to be active in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG7542 in Genome Data Viewer
    Location:
    74D4-74D4; 3-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17549826..17550980)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17542926..17544080)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45165 Neighboring gene Nedd4 Neighboring gene Jonah 74E Neighboring gene Cyclin T Neighboring gene Ecdysone-induced protein 74EF

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Comm function in commissural axon guidance: cell-autonomous sorting of Robo in vivo. Keleman K, et al. Nat Neurosci, 2005 Feb. PMID 15657595
    2. Drosophila melanogaster tPlus3a and tPlus3b ensure full male fertility by regulating transcription of Y-chromosomal, seminal fluid, and heat shock genes. Hundertmark T, et al. PLoS One, 2019. PMID 30845228, Free PMC Article
    3. Quality of regulatory elements in Drosophila retrogenes. Bai Y, et al. Genomics, 2009 Jan. PMID 18848618, Free PMC Article
    4. Transient adult microbiota, gut homeostasis and longevity: novel insights from the Drosophila model. Erkosar B, et al. FEBS Lett, 2014 Nov 17. PMID 24983497
    5. A transcriptomics assessment of oxygen-temperature interactions reveals novel candidate genes underlying variation in thermal tolerance and survival. Boardman L, et al. J Insect Physiol, 2018 Apr. PMID 29038013

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG7542-PA
    CG7542-PB
    NP_001287099.1
    NP_648995.3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17549826..17550980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300170.1 → NP_001287099.1  uncharacterized protein Dmel_CG7542, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287099.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4A8, Q9VVI5
      Conserved Domains (2) summary
      smart00020
      Location:27 → 260
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:27 → 263
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    2. NM_140738.2 → NP_648995.3  uncharacterized protein Dmel_CG7542, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648995.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4A8, Q9VVI5
      Related
      FBpp0074946, FBtr0075181
      Conserved Domains (2) summary
      smart00020
      Location:27 → 260
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:27 → 263
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T4A8 Q8T4A8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools