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    CG14644 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40536, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14644provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0250821
    Locus tag
    Dmel_CG14644
    See related
    AllianceGenome:FB:FBgn0250821
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14644; NEST:bs06h05
    Summary
    Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14644 in Genome Data Viewer
    Location:
    82A1-82A1; 3-47.1 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4251894..4253043, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (77616..78765, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene TweedleF Neighboring gene TweedleG Neighboring gene TweedleV Neighboring gene Odorant receptor 82a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genes Relocated Between Drosophila Chromosome Arms Evolve Under Relaxed Selective Constraints Relative to Non-Relocated Genes. Hart MLI, et al. J Mol Evol, 2018 Jul. PMID 29926120
    2. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    3. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14644-PA
    CG14644-PB
    NEST:bs06h05

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      4251894..4253043 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141188.5 → NP_649445.3  uncharacterized protein Dmel_CG14644, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649445.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4B6, Q9VMZ7
      Related
      FBpp0078620
      Conserved Domains (2) summary
      smart00244
      Location:64 → 223
      PHB; prohibitin homologues
      cl19107
      Location:89 → 292
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    2. NM_001275317.1 → NP_001262246.1  uncharacterized protein Dmel_CG14644, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262246.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFI9
      Conserved Domains (2) summary
      smart00244
      Location:2 → 155
      PHB; prohibitin homologues
      cl19107
      Location:21 → 224
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFI9 A0A0B4KFI9
    Q8T4B6 Q8T4B6

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