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    Ktch Ketchup [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43681, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ktchprovided by FlyBase
    Official Full Name
    Ketchupprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039821
    Locus tag
    Dmel_CG15556
    See related
    AllianceGenome:FB:FBgn0039821
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0170980.178; anon-WO0170980.179; AT07595p; CG15556; Dmel\CG15556
    Summary
    Predicted to enable G protein-coupled receptor activity and mechanoreceptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Is active in plasma membrane. Is expressed in adult head. Orthologous to human ADGRG7 (adhesion G protein-coupled receptor G7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ktch in Genome Data Viewer
    Location:
    100B3-100B3; 3-102 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31127965..31130666, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26953687..26956388, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Proteasome alpha3 subunit, Testis-specific Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46207 Neighboring gene long non-coding RNA:CR43458

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Parallel Genomic Engineering of Two Drosophila Genes Using Orthogonal attB/attP Sites. Blanco-Redondo B, et al. G3 (Bethesda), 2018 Aug 30. PMID 30065043, Free PMC Article
    2. The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila. Vieira Contreras F, et al. Cell Rep, 2024 Jan 23. PMID 38180839
    3. Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation. Scholz N, et al. Nature, 2023 Mar. PMID 36890234
    4. Comparative genomic analysis and evolution of family-B G protein-coupled receptors from six model insect species. Li C, et al. Gene, 2013 Apr 25. PMID 23428791
    5. Family-B G-protein-coupled receptors. Harmar AJ. Genome Biol, 2001. PMID 11790261, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables G protein-coupled receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables mechanoreceptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ketchup
    Names
    CG15556-PA
    CG15556-PB
    CG15556-PC
    Ktch-PA
    Ktch-PB
    Ktch-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31127965..31130666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143588.2 → NP_651845.2  ketchup, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651845.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4B2, Q9VA10
      Related
      FBpp0085099, FBtr0085737
      Conserved Domains (1) summary
      cl21561
      Location:481 → 703
      7tm_4; Olfactory receptor

    2. NM_001260450.1 → NP_001247379.1  ketchup, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247379.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4B2, Q9VA10
      Conserved Domains (1) summary
      cl21561
      Location:481 → 703
      7tm_4; Olfactory receptor

    3. NM_001260451.1 → NP_001247380.1  ketchup, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247380.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4B2, Q9VA10
      Conserved Domains (1) summary
      cl21561
      Location:481 → 703
      7tm_4; Olfactory receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T4B2 Q8T4B2
    Q9VA10 Q9VA10

    Gene LinkOut

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