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    CG14891 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42013, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14891provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038445
    Locus tag
    Dmel_CG14891
    See related
    AllianceGenome:FB:FBgn0038445
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14891; FBXL13
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14891 in Genome Data Viewer
    Location:
    89B20-89B20; 3-58 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16571515..16573158)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12397237..12398880)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Death executioner caspase related to Apopain/Yama Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46030 Neighboring gene uncharacterized protein Neighboring gene Sarcoplasmic calcium-binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Do candidate genes mediating conspecific sperm precedence affect sperm competitive ability within species? A test case in Drosophila. Civetta A, et al. G3 (Bethesda), 2014 Jul 16. PMID 25031180, Free PMC Article
    2. Expression of Mst89B and CG31287 is Needed for Effective Sperm Storage and Egg Fertilization in Drosophila. Grewal G, et al. Cells, 2021 Feb 1. PMID 33535499, Free PMC Article
    3. F-box proteins: the key to protein degradation. Ho MS, et al. J Biomed Sci, 2006 Mar. PMID 16463014
    4. A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila. Dui W, et al. J Genet Genomics, 2012 Aug 20. PMID 22884096
    5. Functional variants identify sex-specific genes and pathways in Alzheimer's Disease. Bourquard T, et al. Nat Commun, 2023 May 13. PMID 37179358, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14891-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      16571515..16573158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142303.4 → NP_650560.1  uncharacterized protein Dmel_CG14891 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650560.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5RJP6, Q9VET4
      Related
      FBpp0082752
      Conserved Domains (3) summary
      cd09293
      Location:199 → 352
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:239 → 262
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam14259
      Location:25 → 91
      RRM_6; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VET4 Q9VET4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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