Dnali1 Dynein axonemal light intermediate chain 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Dnali1provided by FlyBase
Official Full Name: Dynein axonemal light intermediate chain 1provided by FlyBase
Primary source: FLYBASE:FBgn0037962
Locus tag: Dmel_CG6971
See related: AllianceGenome:FB:FBgn0037962
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0140519.67; CG6971; Dmel\CG6971; DNALI1; IDA-Dnali1
Summary: Predicted to enable dynein heavy chain binding activity. Predicted to be involved in cilium movement and inner dynein arm assembly. Predicted to be located in dynein axonemal particle. Predicted to be part of inner dynein arm. Predicted to be active in axoneme and ciliary base. Is expressed in chordotonal neurons; chordotonal organ precursor cell; spermatogonium; and spermatozoon. Human ortholog(s) of this gene implicated in spermatogenic failure 83. Orthologous to human DNALI1 (dynein axonemal light intermediate chain 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (11892306..11893297, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (7718028..7719019, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

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Function	Evidence Code	Pubs
enables dynein heavy chain binding	IBA Inferred from Biological aspect of Ancestor more info
enables dynein heavy chain binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in cilium movement	ISS Inferred from Sequence or Structural Similarity more info
involved_in inner dynein arm assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in axoneme	IBA Inferred from Biological aspect of Ancestor more info
is_active_in ciliary base	IBA Inferred from Biological aspect of Ancestor more info
located_in dynein axonemal particle	ISS Inferred from Sequence or Structural Similarity more info
part_of inner dynein arm	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain