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    Zfp951 zinc finger protein 951 [ Mus musculus (house mouse) ]

    Gene ID: 626391, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp951provided by MGI
    Official Full Name
    zinc finger protein 951provided by MGI
    Primary source
    MGI:MGI:2441896
    See related
    Ensembl:ENSMUSG00000072774 AllianceGenome:MGI:2441896
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm38611; C230055K05Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 1.6), thymus adult (RPKM 1.1) and 26 other tissues See more
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    Genomic context

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    See Zfp951 in Genome Data Viewer
    Location:
    5 E5; 5 50.68 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (104950112..105007988, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (104802246..104860157, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 pseudogene Neighboring gene taxilin gamma pseudogene Neighboring gene STARR-seq mESC enhancer starr_13838 Neighboring gene STARR-seq mESC enhancer starr_13839 Neighboring gene STARR-seq mESC enhancer starr_13840 Neighboring gene STARR-seq mESC enhancer starr_13841 Neighboring gene STARR-seq mESC enhancer starr_13842 Neighboring gene STARR-seq mESC enhancer starr_13843 Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 pseudogene Neighboring gene predicted gene, 29714

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    kruppel-related zinc finger protein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039231.3 → NP_001034320.3  kruppel-related zinc finger protein-like

      Status: VALIDATED

      Source sequence(s)
      AC110537, AK132470, BY735223, CD807221
      Consensus CDS
      CCDS80351.1
      UniProtKB/TrEMBL
      A0A087WRH0
      Related
      ENSMUSP00000140625.2, ENSMUST00000186219.7
      Conserved Domains (5) summary
      smart00349
      Location:28 → 69
      KRAB; krueppel associated box
      COG5048
      Location:286 → 439
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:290 → 310
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:28 → 64
      KRAB; KRAB box
      pfam13465
      Location:358 → 382
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. NR_155269.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC110537

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      104950112..105007988 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165401.1 → XP_036021294.1  kruppel-related zinc finger protein-like isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:300 → 453
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:304 → 324
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:42 → 82
      KRAB; KRAB box

    2. XM_036165402.1 → XP_036021295.1  kruppel-related zinc finger protein-like isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:271 → 424
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:275 → 295
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 53
      KRAB; KRAB box

    3. XM_030254749.2 → XP_030110609.1  kruppel-related zinc finger protein-like isoform X2

      Conserved Domains (3) summary
      COG5048
      Location:271 → 424
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:275 → 295
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 53
      KRAB; KRAB box

    4. XM_036165403.1 → XP_036021296.1  kruppel-related zinc finger protein-like isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:230 → 383
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:234 → 254
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RNA

    1. XR_004942546.1 RNA Sequence

    2. XR_003955690.2 RNA Sequence

    3. XR_001784732.3 RNA Sequence

    4. XR_003955688.2 RNA Sequence

    5. XR_003955689.1 RNA Sequence

    6. XR_003955687.1 RNA Sequence

    7. XR_004942547.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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