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    Dmrtc1b DMRT-like family C1b [ Mus musculus (house mouse) ]

    Gene ID: 632708, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dmrtc1bprovided by MGI
    Official Full Name
    DMRT-like family C1bprovided by MGI
    Primary source
    MGI:MGI:3639121
    See related
    Ensembl:ENSMUSG00000073027 AllianceGenome:MGI:3639121
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm714; Dmrt8.2
    Summary
    Predicted to be active in nucleus. Is expressed in gonad; mesonephros; ovary; and testis. Orthologous to human DMRTC1B (DMRT like family C1B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 8.9) See more
    Orthologs
    human all
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    Genomic context

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    See Dmrtc1b in Genome Data Viewer
    Location:
    X D; X 45.66 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (101751487..101758815)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (102707881..102715209)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene high mobility group box 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_47676 Neighboring gene family with sequence similarity 236, member F Neighboring gene STARR-seq mESC enhancer starr_47677 Neighboring gene ornithine decarboxylase, structural 1 pseudogene Neighboring gene predicted pseudogene 9119 Neighboring gene STARR-seq mESC enhancer starr_47678

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Male-biased expression of X-chromosomal DM domain-less Dmrt8 genes in the mouse. Veith AM, et al. Genomics, 2006 Aug. PMID 16488114
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NOT enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    NOT enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DMRT-like family C1b
    Names
    doublesex and mab-3 related transcription factor 8.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039116.2 → NP_001034205.2  DMRT-like family C1b isoform 2

      See identical proteins and their annotated locations for NP_001034205.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      BC150829, DQ316776
      Consensus CDS
      CCDS30325.1
      UniProtKB/TrEMBL
      A2AI93, Q2PMX8
      Related
      ENSMUSP00000098880.3, ENSMUST00000101324.9
      Conserved Domains (1) summary
      pfam15791
      Location:114 → 239
      DMRT-like; Doublesex-and mab-3-related transcription factor C1 and C2

    2. NM_001310614.1 → NP_001297543.1  DMRT-like family C1b isoform 1

      See identical proteins and their annotated locations for NP_001297543.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
      Source sequence(s)
      DQ316777
      Consensus CDS
      CCDS81160.1
      UniProtKB/TrEMBL
      Q2PMX6, Q2PMX8
      Related
      ENSMUSP00000109239.2, ENSMUST00000113609.8
      Conserved Domains (1) summary
      pfam15791
      Location:140 → 265
      DMRT-like; Doublesex-and mab-3-related transcription factor C1 and C2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      101751487..101758815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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