Svs3a seminal vesicle secretory protein 3A [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Svs3aprovided by RGD
Full Name: seminal vesicle secretory protein 3Aprovided by RGD
Primary source: RGD:708390
See related: EnsemblRapid:ENSRNOG00000062737 AllianceGenome:RGD:708390
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Svs3
Summary: Predicted to be involved in sperm capacitation. Predicted to be located in extracellular region. Orthologous to human SEMG1 (semenogelin 1) and SEMG2 (semenogelin 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 3q42

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (173377977..173383302)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (152961706..152963922)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	Unplaced Scaffold	NW_007906879.1 (28118..30334)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Six peptide sequences determined from the trypsin digests of RSVS III were confirmed in the protein sequence derived from two paralogs, RSVS III(alpha) and RSVS III(beta) gene, in rat 3q42 [RSVS III(alpha) and RSVS III(beta)]
Title: Functional preservation of duplicated pair for RSVS III gene in the REST locus of rat 3q42.

Submit: New GeneRIF Correction

General gene information

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Markers

BF417389 (e-PCR)
- UniSTS:249676

NoName (e-PCR)
- UniSTS:493154

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in coagulation	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of flagellated sperm motility	IEA Inferred from Electronic Annotation more info
involved_in sperm capacitation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: seminal vesicle secretory protein 3A

Names: androgen-responsive protein pSv-1; seminal vesicle secretion 3 alpha; seminal vesicle secretory protein 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.