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    Trappc6b trafficking protein particle complex subunit 6B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299075, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Trappc6bprovided by RGD
    Official Full Name
    trafficking protein particle complex subunit 6Bprovided by RGD
    Primary source
    RGD:1309325
    See related
    EnsemblRapid:ENSRNOG00000004103 AllianceGenome:RGD:1309325
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309325
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be part of TRAPP complex. Predicted to be active in cis-Golgi network and trans-Golgi network. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy. Orthologous to human TRAPPC6B (trafficking protein particle complex subunit 6B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 199.6), Brain (RPKM 184.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Trappc6b in Genome Data Viewer
    Location:
    6q23
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (82475794..82486928, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (76740898..76752035, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (80142126..80153216, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 51, subfamily a, polypeptide 1, pseudogene 1 Neighboring gene U2 spliceosomal RNA like 3 Neighboring gene pinin, desmosome associated protein Neighboring gene MIA SH3 domain ER export factor 2 Neighboring gene small nucleolar RNA, H/ACA box 26 like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of TRAPP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cis-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    trafficking protein particle complex subunit 6B
    Names
    trafficking protein particle complex 6B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106733.1 → NP_001100203.1  trafficking protein particle complex subunit 6B

      See identical proteins and their annotated locations for NP_001100203.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473947
      UniProtKB/TrEMBL
      A6HBR1, D3ZES2
      Related
      ENSRNOP00000005568.4, ENSRNOT00000005568.7
      Conserved Domains (1) summary
      cd14944
      Location:3 → 156
      TRAPPC6A_Trs33; Trs33 subunit of the TRAPP complex

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      82475794..82486928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261678.1 → XP_063117748.1  trafficking protein particle complex subunit 6B isoform X1

    2. XM_039111978.2 → XP_038967906.1  trafficking protein particle complex subunit 6B isoform X2

      UniProtKB/TrEMBL
      A0A8I6GH06
      Related
      ENSRNOP00000104838.1, ENSRNOT00000163699.1
      Conserved Domains (1) summary
      cd14944
      Location:3 → 117
      TRAPPC6A_Trs33; Trs33 subunit of the TRAPP complex
    Nucleotide Protein Strain
    Heading Accession and Version

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