Bmyc brain expressed myelocytomatosis oncogene [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Bmycprovided by RGD
Official Full Name: brain expressed myelocytomatosis oncogeneprovided by RGD
Primary source: RGD:1584970
See related: EnsemblRapid:ENSRNOG00000042556 AllianceGenome:RGD:1584970
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Mycb; B-myc
Summary: Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus and spindle. Human ortholog(s) of this gene implicated in several diseases, including angiosarcoma; demyelinating disease; hematologic cancer (multiple); lung adenocarcinoma; and prostate cancer (multiple). Orthologous to human MYC (MYC proto-oncogene, bHLH transcription factor). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 3p13

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (28910689..28911448)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (8512569..8513328)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (2916662..2917421)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH129186 (e-PCR)
- UniSTS:212494

AW060705 (e-PCR)
- UniSTS:178588

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in spindle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein B-Myc

Names: Bmyc protein (AA 1-178); avian myelocytomatosis viral (v-myc) related oncogene; transforming protein B-Myc

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.