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    ssuh2rs1 ssu-2 homolog, related sequence 1 [ Danio rerio (zebrafish) ]

    Gene ID: 767720, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ssuh2rs1provided by ZNC
    Official Full Name
    ssu-2 homolog, related sequence 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-994
    See related
    Ensembl:ENSDARG00000063292 AllianceGenome:ZFIN:ZDB-GENE-060929-994
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ssuh2; wu:fc17d03; zgc:153440
    Summary
    Acts upstream of or within odontogenesis. Predicted to be located in nucleus. Is expressed in ceratobranchial 5 tooth and gut. Orthologous to human SSUH2 (ssu-2 homolog). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See ssuh2rs1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (7311661..7349243)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (7292752..7329931)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 6a Neighboring gene glutamate receptor interacting protein 2a Neighboring gene selenoprotein H Neighboring gene histone H3-like centromeric protein A Neighboring gene proprotein convertase subtilisin/kexin type 1 inhibitor, like Neighboring gene LHFPL tetraspan subfamily member 4b Neighboring gene histone deacetylase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I. Xiong F, et al. Hum Mutat, 2017 Jan. PMID 27680507
    2. Modulation of tissue repair by regeneration enhancer elements. Kang J, et al. Nature, 2016 Apr 14. PMID 27049946, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC153440

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within odontogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    protein SSUH2 homolog
    Names
    protein ssu-2 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076658.1 → NP_001070126.1  protein SSUH2 homolog

      See identical proteins and their annotated locations for NP_001070126.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124353
      UniProtKB/Swiss-Prot
      A0A0R4IG68, F1QCJ3, Q08C76
      Related
      ENSDARP00000086779.5, ENSDART00000092347.7
      Conserved Domains (1) summary
      cl21539
      Location:174 → 221
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      7311661..7349243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005166701.5 → XP_005166758.1  protein SSUH2 homolog isoform X1

      UniProtKB/Swiss-Prot
      A0A0R4IG68, F1QCJ3, Q08C76
      UniProtKB/TrEMBL
      A0A8M2BE58
      Conserved Domains (1) summary
      cl21539
      Location:215 → 262
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08C76.2 GenPept UniProtKB/Swiss-Prot:Q08C76

    Gene LinkOut

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