tnnc2.2 troponin C2, fast skeletal type, tandem duplicate 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tnnc2.2provided by ZNC
Official Full Name: troponin C2, fast skeletal type, tandem duplicate 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-000322-2
See related: Ensembl:ENSDARG00000070835 AllianceGenome:ZFIN:ZDB-GENE-000322-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tnnc; tnnc2; wu:fb39a12
Summary: Predicted to enable calcium ion binding activity. Acts upstream of or within response to activity. Predicted to be part of troponin complex. Is expressed in fast muscle cell; head muscle; heart tube; skeletal muscle; and skeletal muscle cell. Human ortholog(s) of this gene implicated in congenital myopathy 15. Orthologous to human TNNC2 (troponin C2, fast skeletal type). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (20422675..20427296)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (20496332..20500953)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to activity	IDA Inferred from Direct Assay more info	PubMed
involved_in skeletal muscle contraction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of troponin complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: troponin C, skeletal muscle

Names: fsTnC; troponin C type 2 (fast); troponin C, fast skeletal

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.