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    csrB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847719, updated on 3-Dec-2024

    Summary

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    Official Symbol
    csrB
    Primary source
    ECOCYC:G0-8785
    Locus tag
    b4408
    See related
    ASAP:ABE-0047213
    Gene type
    ncRNA
    RNA name
    other
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2787
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    Genomic context

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    Sequence:
    NC_000913.3 (2924156..2924524, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative flavodoxin YqcA Neighboring gene tRNA pseudouridine(65) synthase Neighboring gene DUF446 domain-containing protein YqcC Neighboring gene SecY-interacting protein Neighboring gene 7-cyano-7-deazaguanine reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effects of the two-component system comprising GacA and GacS of Erwinia carotovora subsp. carotovora on the production of global regulatory rsmB RNA, extracellular enzymes, and harpinEcc. Cui Y, et al. Mol Plant Microbe Interact, 2001 Apr. PMID 11310739
    2. Characterization of two novel regulatory genes affecting Salmonella invasion gene expression. Altier C, et al. Mol Microbiol, 2000 Feb. PMID 10672185
    3. CsrB sRNA family: sequestration of RNA-binding regulatory proteins. Babitzke P, et al. Curr Opin Microbiol, 2007 Apr. PMID 17383221
    4. Molecular characterization of global regulatory RNA species that control pathogenicity factors in Erwinia amylovora and Erwinia herbicola pv. gypsophilae. Ma W, et al. J Bacteriol, 2001 Mar. PMID 11222584, Free PMC Article
    5. A regulatory RNA (PrrB RNA) modulates expression of secondary metabolite genes in Pseudomonas fluorescens F113. Aarons S, et al. J Bacteriol, 2000 Jul. PMID 10869066, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CsrD evolution was driven by the selective advantage of decoupling Csr small RNA decay from CsrA binding, connecting it instead to the availability of a preferred carbon source.
      Title: Antagonistic control of the turnover pathway for the global regulatory sRNA CsrB by the CsrA and CsrD proteins.
    2. CsrA binds to the regulatory small RNAs (sRNAs) CsrB and CsrC, which antagonize its activity.
      Title: Circuitry Linking the Catabolite Repression and Csr Global Regulatory Systems of Escherichia coli.
    3. Data indicate that CsrA proteins are sequestered by CsrB noncoding RNAs, and the degradation of CsrB RNAs is increased by CsrD proteins.
      Title: Rapid and robust signaling in the CsrA cascade via RNA-protein interactions and feedback regulation.
    4. CsrA and DksA are both necessary for full expression of csrB and csrC.
      Title: Circuitry linking the Csr and stringent response global regulatory systems.
    5. The expression of the CsrB and and CsrC is controlled by the amino acid availability in the growth medium.
      Title: The Escherichia coli CsrB and CsrC small RNAs are strongly induced during growth in nutrient-poor medium.
    Submit: New GeneRIF Correction

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