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    SPAAR small regulatory polypeptide of amino acid response [ Homo sapiens (human) ]

    Gene ID: 158376, updated on 27-Nov-2024

    Summary

    Official Symbol
    SPAARprovided by HGNC
    Official Full Name
    small regulatory polypeptide of amino acid responseprovided by HGNC
    Primary source
    HGNC:HGNC:27244
    See related
    Ensembl:ENSG00000235387 MIM:617627; AllianceGenome:HGNC:27244
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SPAR; LINC00961
    Summary
    Involved in cellular response to amino acid stimulus and negative regulation of TORC1 signaling. Located in late endosome membrane and lysosomal proton-transporting V-type ATPase complex. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in fat (RPKM 6.4), testis (RPKM 5.2) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See SPAAR in Genome Data Viewer
    Location:
    9p13.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (35909490..35911686)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (35930192..35932388)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (35909487..35911683)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902149 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:35904865-35905746 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:35910159-35911039 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19884 Neighboring gene histidine rich carboxyl terminus 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:35917525-35917666 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr9:35923268-35924467 Neighboring gene phosphoglycerate mutase 1 pseudogene 2 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:35951260-35952459 Neighboring gene olfactory receptor family 2 subfamily S member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General protein information

    Preferred Names
    small regulatory polypeptide of amino acid response
    Names
    long intergenic non-protein coding RNA 961
    small regulatory polypeptide of amino acids response

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001348107.3NP_001335036.2  small regulatory polypeptide of amino acid response

      Status: VALIDATED

      Source sequence(s)
      AA807870, AK056723, AL135841, BC113682
      Consensus CDS
      CCDS94407.1
      Related
      ENSP00000490187.1, ENST00000443779.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      35909490..35911686
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      35930192..35932388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)