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    Sdr39u1 short chain dehydrogenase/reductase family 39U, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 654795, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Sdr39u1provided by MGI
    Official Full Name
    short chain dehydrogenase/reductase family 39U, member 1provided by MGI
    Primary source
    MGI:MGI:1916876
    See related
    Ensembl:ENSMUSG00000022223 AllianceGenome:MGI:1916876
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310014G06Rik
    Summary
    Predicted to enable oxidoreductase activity. Orthologous to human SDR39U1 (short chain dehydrogenase/reductase family 39U member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 39.4), kidney adult (RPKM 36.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Sdr39u1 in Genome Data Viewer
    Location:
    14 C3; 14 28.19 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (56134742..56137802, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (55897283..55900342, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene NYN domain and retroviral integrase containing Neighboring gene STARR-positive B cell enhancer ABC_E7318 Neighboring gene STARR-positive B cell enhancer ABC_E7319 Neighboring gene cerebellin 3 precursor protein Neighboring gene KH and NYN domain containing Neighboring gene STARR-seq mESC enhancer starr_36786 Neighboring gene chymase 1, mast cell Neighboring gene mast cell protease, pseudogene 1 Neighboring gene chymase 2, mast cell

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry. Dai J, et al. J Proteome Res, 2007 Jan. PMID 17203969
    2. Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolution. Gallwitz M, et al. Immunogenetics, 2006 Aug. PMID 16807745
    3. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    epimerase family protein SDR39U1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082975.1 → NP_001076444.1  epimerase family protein SDR39U1 isoform 1

      See identical proteins and their annotated locations for NP_001076444.1

      Status: VALIDATED

      Source sequence(s)
      AI843700, AK049709, BY127480
      Consensus CDS
      CCDS36935.1
      UniProtKB/Swiss-Prot
      Q3V467, Q5M8N4, Q8BWX0
      Related
      ENSMUSP00000106957.4, ENSMUST00000111325.5
      Conserved Domains (1) summary
      cd05242
      Location:2 → 292
      SDR_a8; atypical (a) SDRs, subgroup 8

    2. NM_001374224.1 → NP_001361153.1  epimerase family protein SDR39U1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC098877
      Conserved Domains (1) summary
      cl21454
      Location:2 → 185
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      56134742..56137802 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158783.1 → XP_036014676.1  epimerase family protein SDR39U1 isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:2 → 185
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_030247918.2 → XP_030103778.1  epimerase family protein SDR39U1 isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:2 → 185
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. XM_036158782.1 → XP_036014675.1  epimerase family protein SDR39U1 isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:2 → 185
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_036158781.1 → XP_036014674.1  epimerase family protein SDR39U1 isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:2 → 185
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5M8N4.2 GenPept UniProtKB/Swiss-Prot:Q5M8N4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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