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    aus argus [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42531, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ausprovided by FlyBase
    Official Full Name
    argusprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038881
    Locus tag
    Dmel_CG16791
    See related
    AllianceGenome:FB:FBgn0038881
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.78; cg16791; CG16791; Dmel\CG16791; R5_3R:17143989..17145881
    Summary
    Acts upstream of with a positive effect on autophagosome-lysosome fusion. Predicted to be located in membrane. Is expressed in several structures, including adult head; adult optic lobe; brain; embryonic/larval midgut primordium; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See aus in Genome Data Viewer
    Location:
    93D5-93D6; 3-71 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21318300..21349601, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17144022..17175323, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene SIFamide receptor Neighboring gene uncharacterized protein Neighboring gene Heat shock RNA omega Neighboring gene mir-4951 stem loop Neighboring gene pre-mod(mdg4)-H Neighboring gene pre-mod(mdg4)-G Neighboring gene pre-mod(mdg4)-B Neighboring gene pre-mod(mdg4)-I Neighboring gene pre-mod(mdg4)-P Neighboring gene pre-mod(mdg4)-K Neighboring gene pre-mod(mdg4)-L Neighboring gene pre-mod(mdg4)-J Neighboring gene modifier of mdg4 Neighboring gene pre-mod(mdg4)-T Neighboring gene pre-mod(mdg4)-Z Neighboring gene modifier of mdg4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Short and long sleeping mutants reveal links between sleep and macroautophagy. Bedont JL, et al. Elife, 2021 Jun 4. PMID 34085929, Free PMC Article
    2. Ubiquitin proteasome system in circadian rhythm and sleep homeostasis: Lessons from Drosophila. Ukita Y, et al. Genes Cells, 2022 Jun. PMID 35438236, Free PMC Article
    3. Ultraconserved elements in insect genomes: a highly conserved intronic sequence implicated in the control of homothorax mRNA splicing. Glazov EA, et al. Genome Res, 2005 Jun. PMID 15899965, Free PMC Article
    4. Signaling by the engulfment receptor draper: a screen in Drosophila melanogaster implicates cytoskeletal regulators, Jun N-terminal Kinase, and Yorkie. Fullard JF, et al. Genetics, 2015 Jan. PMID 25395664, Free PMC Article
    5. Rapid Changes in the Translatome during the Conversion of Growth Cones to Synaptic Terminals. Zhang KX, et al. Cell Rep, 2016 Feb 9. PMID 26832407

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Short and long sleeping mutants reveal links between sleep and macroautophagy.
      Title: Short and long sleeping mutants reveal links between sleep and macroautophagy.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in autophagosome-lysosome fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_positive_effect autophagosome-lysosome fusion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    argus
    Names
    CG16791-PA
    CG16791-PB
    CG16791-PC
    CG16791-PD
    aus-PA
    aus-PB
    aus-PC
    aus-PD
    NP_001287441.1
    • unusual splice
    NP_650967.2
    • unusual splice

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      21318300..21349601 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300514.1 → NP_001287443.1  argus, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287443.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LIF6

    2. NM_142710.4 → NP_650967.2  argus, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650967.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q867H8, Q9VDB7
      Related
      FBpp0083494

    3. NM_001300512.1 → NP_001287441.1  argus, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287441.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LHQ0

    4. NM_001300513.1 → NP_001287442.1  argus, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287442.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LHH8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LHH8 A0A0B4LHH8
    A0A0B4LHQ0 A0A0B4LHQ0
    A0A0B4LIF6 A0A0B4LIF6
    Q9VDB7 Q9VDB7

    Gene LinkOut

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