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    Sclp sclp [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32156, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sclpprovided by FlyBase
    Official Full Name
    sclpprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030357
    Locus tag
    Dmel_CG2471
    See related
    AllianceGenome:FB:FBgn0030357
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2471; CT8171; Dmel\CG2471; dSCLP
    Summary
    Involved in muscle system process. Is expressed in larval somatic muscle cell. Orthologous to human LRRC20 (leucine rich repeat containing 20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Sclp in Genome Data Viewer
    Location:
    10F6-10F7; 1-37 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11920004..11924662, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11814037..11818695, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR32661 Neighboring gene long non-coding RNA:CR43157 Neighboring gene long non-coding RNA:CR32660 Neighboring gene PDZ domain containing 8 Neighboring gene cacophony

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Single-cell transcriptome sequencing reveals Wolbachia-mediated modification in early stages of Drosophila spermatogenesis. Dou W, et al. Proc Biol Sci, 2023 Jan 11. PMID 36629101, Free PMC Article
    2. Wispy, the Drosophila homolog of GLD-2, is required during oogenesis and egg activation. Cui J, et al. Genetics, 2008 Apr. PMID 18430932, Free PMC Article
    3. Differences in Postmating Transcriptional Responses between Conspecific and Heterospecific Matings in Drosophila. Ahmed-Braimah YH, et al. Mol Biol Evol, 2021 Mar 9. PMID 33035303, Free PMC Article
    4. Germline-dependent gene expression in distant non-gonadal somatic tissues of Drosophila. Parisi MJ, et al. BMC Genomics, 2010 Jun 1. PMID 20515475, Free PMC Article
    5. Computational identification of Ftz/Ftz-F1 downstream target genes. Bowler T, et al. Dev Biol, 2006 Nov 1. PMID 16996052

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in muscle system process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in muscle system process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    sclp
    Names
    CG2471-PA
    CG2471-PB
    CG2471-PC
    Sclp-PA
    Sclp-PB
    Sclp-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      11920004..11924662 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272546.1 → NP_001259475.1  sclp, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259475.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H0RNK3
      Conserved Domains (3) summary
      cd00116
      Location:77 → 232
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:93 → 115
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:140 → 198
      LRR_8; Leucine rich repeat

    2. NM_132542.3 → NP_572770.1  sclp, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572770.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYS0
      Related
      FBpp0073430
      Conserved Domains (3) summary
      cd00116
      Location:77 → 232
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:93 → 115
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:140 → 198
      LRR_8; Leucine rich repeat

    3. NM_001169256.1 → NP_001162727.1  sclp, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162727.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0PV74
      Conserved Domains (2) summary
      sd00033
      Location:20 → 41
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:66 → 124
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    C0PV74 C0PV74
    H0RNK3 H0RNK3
    Q9VYS0 Q9VYS0

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