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    GstE7 Glutathione S transferase E7 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37112, updated on 9-Dec-2024

    Summary

    Official Symbol
    GstE7provided by FlyBase
    Official Full Name
    Glutathione S transferase E7provided by FlyBase
    Primary source
    FLYBASE:FBgn0063493
    Locus tag
    Dmel_CG17531
    See related
    AllianceGenome:FB:FBgn0063493
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17531; Dmel\CG17531; DmGSTE7; E7; GST-E7; gste7; gstE7; GSTE7
    Summary
    Enables glutathione peroxidase activity and glutathione transferase activity. Involved in glutathione metabolic process. Predicted to be located in cytoplasm. Is expressed in anterior midgut primordium; embryonic/larval midgut; organism; and posterior midgut primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See GstE7 in Genome Data Viewer
    Location:
    55C7-55C7; 2-85 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18406924..18407688)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14294429..14295193)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Glutathione S transferase E5 Neighboring gene Glutathione S transferase E6 Neighboring gene Glutathione S transferase E8 Neighboring gene Glutathione S transferase E9 Neighboring gene immune deficiency

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glutathione peroxidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glutathione transferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glutathione metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    glutathione S transferase E7
    Names
    CG17531-PA
    GstE7-PA
    glutathione S-transferase
    glutathione transferase E7
    NP_611329.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18406924..18407688
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137485.4NP_611329.1  glutathione S transferase E7 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611329.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZB72, Q8MR33
      Related
      FBpp0085856
      Conserved Domains (3) summary
      cd03177
      Location:91209
      GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
      COG0625
      Location:4196
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03045
      Location:477
      GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...