U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Pcp Pupal cuticle protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33985, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Pcpprovided by FlyBase
    Official Full Name
    Pupal cuticle proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003046
    Locus tag
    Dmel_CG3440
    See related
    AllianceGenome:FB:FBgn0003046
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3440; DMCPGART; DmelPcp; Dmel\CG3440; Gart; PCP-Gart; Pcpgart
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle and structural constituent of pupal chitin-based cuticle. Involved in imaginal disc fusion, thorax closure. Predicted to be active in chitin-based extracellular matrix. Is expressed in larval abdomen. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Pcp in Genome Data Viewer
    Location:
    27D4-27D4; 2-24 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7021682..7022470)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7021682..7022470)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene GART trifunctional enzyme Neighboring gene uncharacterized protein Neighboring gene Mitochondrial Magnesium Exporter 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Unusual organizational features of the Drosophila Gart locus are not conserved within Diptera. Clark DV, et al. J Mol Evol, 1992 Jul. PMID 1518084
    2. Gene within a gene: nested Drosophila genes encode unrelated proteins on opposite DNA strands. Henikoff S, et al. Cell, 1986 Jan 17. PMID 3079672
    3. Conserved arrangement of nested genes at the Drosophila Gart locus. Henikoff S, et al. Genetics, 1987 Dec. PMID 3123310, Free PMC Article
    4. The cuticle genes of drosophila: a developmentally regulated gene cluster. Snyder M, et al. Cell, 1981 Jul. PMID 6168386
    5. Broad specifies pupal development and mediates the 'status quo' action of juvenile hormone on the pupal-adult transformation in Drosophila and Manduca. Zhou X, et al. Development, 2002 May. PMID 11959833

    See all (50) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables structural constituent of pupal chitin-based cuticle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables structural constituent of pupal chitin-based cuticle TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in imaginal disc fusion, thorax closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    pupal cuticle protein
    Names
    CG3440-PA
    Pcp-PA
    gart intron gene
    gart intronic gene

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7021682..7022470
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057325.3 → NP_476673.1  pupal cuticle protein [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476673.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8WHK2, P14484, Q9VM52
      Related
      FBpp0079016
      Conserved Domains (1) summary
      pfam00379
      Location:45 → 92
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P14484.1 P14484

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools