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    Polr2F RNA polymerase II, I and III subunit F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 48312, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Polr2Fprovided by FlyBase
    Official Full Name
    RNA polymerase II, I and III subunit Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003275
    Locus tag
    Dmel_CG1163
    See related
    AllianceGenome:FB:FBgn0003275
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH21608; CG1163; Dm6; Dmel\CG1163; H5; pol II; Pol II; polII; PolII; RNA pol II; RNA Pol II; RNA polII; RNA polymerase II; RNAP; RNAP II; RNApolII; RpABC14; RPB6; RPB6_DROME; rpII18; RpII18; RPII18; Rpll18; RPO26
    Summary
    Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Part of RNA polymerase II, core complex. Orthologous to human POLR2F (RNA polymerase II, I and III subunit F). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Polr2F in Genome Data Viewer
    Location:
    83A1-83A1; 3-47.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5371795..5372397)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1197517..1198119)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44103 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene humpty dumpty Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Paternal transmission of mitochondrial DNA as an integral part of mitochondrial inheritance in metapopulations of Drosophila simulans. Wolff JN, et al. Heredity (Edinb), 2013 Jan. PMID 23010820, Free PMC Article
    2. Comparative analysis of four parameters involved in puffing activity along chromosome arm 2L of D melanogaster. Visa N, et al. Biol Cell, 1991. PMID 1726421
    3. A Drosophila anti-RNA polymerase II antibody recognizes a plant nucleolar antigen, RNA polymerase I, which is mostly localized in fibrillar centres. Martin M, et al. J Cell Sci, 1991 Sep. PMID 1795033
    4. Determination of Coxiella burnetii rpoB sequence and its use for phylogenetic analysis. Mollet C, et al. Gene, 1998 Jan 19. PMID 9511749
    5. Reverse genetics of Drosophila RNA polymerase II: identification and characterization of RpII140, the genomic locus for the second-largest subunit. Hamilton BJ, et al. Genetics, 1993 Jun. PMID 8325487, Free PMC Article

    See all (97) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to RNA polymerase I activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase I activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    contributes_to RNA polymerase II activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase II activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    contributes_to RNA polymerase III activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase III activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA transcription by RNA polymerase III ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription by RNA polymerase I ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase I complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase II, core complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of RNA polymerase II, core complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase III complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNA polymerase II, I and III subunit F
    Names
    CG1163-PA
    Polr2F-PA
    RNA polymerase II
    RNA polymerase II (18-kDa subunit)
    RNA polymerase II 18kD subunit
    RNA-polymerase ABC 14kD subunit
    NP_524910.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5371795..5372397
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080171.4 → NP_524910.1  RNA polymerase II, I and III subunit F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524910.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24320, Q9VNA7
      UniProtKB/TrEMBL
      A0A1B2AK96
      Related
      FBpp0078433
      Conserved Domains (1) summary
      PLN00152
      Location:27 → 130
      PLN00152; DNA-directed RNA polymerase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q24320.1 Q24320

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