Ugt37C1 UDP-glycosyltransferase family 37 member C1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Ugt37C1provided by FlyBase
Official Full Name: UDP-glycosyltransferase family 37 member C1provided by FlyBase
Primary source: FLYBASE:FBgn0026754
Locus tag: Dmel_CG8652
See related: AllianceGenome:FB:FBgn0026754
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: AC 004641A; CG8652; Dmel\CG8652; DmeUgt37c1; EG:EG0003.4; LD15335; ugt37C1; Ugt37c1; UGT37C1
Summary: Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation and sterol metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (16843296..16845038, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (12730801..12732543, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables UDP-glycosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables UDP-glycosyltransferase activity	ISM Inferred from Sequence Model more info	PubMed

Process	Evidence Code	Pubs
involved_in glycosylation	ISM Inferred from Sequence Model more info	PubMed
involved_in sterol metabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	ISM Inferred from Sequence Model more info	PubMed
located_in membrane	ISM Inferred from Sequence Model more info	PubMed