Gr2a Gustatory receptor 2a [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gr2aprovided by FlyBase
Official Full Name: Gustatory receptor 2aprovided by FlyBase
Primary source: FLYBASE:FBgn0265139
Locus tag: Dmel_CG18531
See related: AllianceGenome:FB:FBgn0265139
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG18531; Dmel\CG18531; EG:BACN32G11.1; GR1F.1; Gr1F1; GR2a; Gr2B1; GR2B1
Summary: Predicted to enable G protein-coupled receptor activity; ligand-gated monoatomic ion channel activity; and taste receptor activity. Predicted to be involved in several processes, including chemosensory behavior; male courtship behavior; and sensory perception of taste. Predicted to be located in membrane. Predicted to be active in several cellular components, including axon; dendrite; and neuronal cell body. Is expressed in several structures, including adult abdomen; adult mouth; embryonic/larval gustatory receptor neurons; gnathal ganglion; and sense organ. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (1452430..1454177)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (1346463..1348210)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

The gustatory receptor Gr2a is expressed in the pharyngeal neurons and is necessary for feeding inhibition.
Title: Involvement of a Gr2a-Expressing Drosophila Pharyngeal Gustatory Receptor Neuron in Regulation of Aversion to High-Salt Foods.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables ligand-gated monoatomic ion channel activity	ISS Inferred from Sequence or Structural Similarity more info
enables taste receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables taste receptor activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in chemosensory behavior	IBA Inferred from Biological aspect of Ancestor more info
involved_in detection of chemical stimulus involved in sensory perception of taste	NAS Non-traceable Author Statement more info	PubMed
involved_in male courtship behavior	IBA Inferred from Biological aspect of Ancestor more info
involved_in monoatomic ion transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in sensory perception of taste	IEA Inferred from Electronic Annotation more info
involved_in sensory perception of taste	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in sensory perception of taste	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
is_active_in axon	IBA Inferred from Biological aspect of Ancestor more info
is_active_in dendrite	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in neuronal cell body	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

Names: CG18531-PB; CG18531-PC; Gr2a-PB; Gr2a-PC; gustatory receptor 1F.1; gustatory receptor 2B1

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