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    CG4789 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32668, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4789provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030792
    Locus tag
    Dmel_CG4789
    See related
    AllianceGenome:FB:FBgn0030792
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4789; Q9VXA9
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be active in endomembrane system. Is expressed in organism. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RABL3 (RAB, member of RAS oncogene family like 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4789 in Genome Data Viewer
    Location:
    15A9-15A9; 1-55 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16800930..16802000)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16694963..16696033)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene SIN3-associated polypeptide 30 Neighboring gene Rrp45 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Rat1 Interacting Protein 1 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44053 Neighboring gene pickpocket 28

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins. Lu Z, et al. Genome Biol, 2014 Jan 7. PMID 24393626, Free PMC Article
    2. Nociceptor-Enriched Genes Required for Normal Thermal Nociception. Honjo K, et al. Cell Rep, 2016 Jul 12. PMID 27346357, Free PMC Article
    3. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047, Free PMC Article
    4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4789-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16800930..16802000
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132938.4 → NP_573166.1  uncharacterized protein Dmel_CG4789 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573166.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZD5, Q9VXA9
      Related
      FBpp0074107
      Conserved Domains (1) summary
      cl21455
      Location:7 → 228
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXA9 Q9VXA9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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