U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG1695 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33046, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG1695provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031116
    Locus tag
    Dmel_CG1695
    See related
    AllianceGenome:FB:FBgn0031116
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1695
    Summary
    Predicted to enable GTPase activator activity. Orthologous to human SGSM1 (small G protein signaling modulator 1) and SGSM2 (small G protein signaling modulator 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG1695 in Genome Data Viewer
    Location:
    19D1-19D1; 1-64 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20433950..20445599)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20304977..20316626)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene maroon-like Neighboring gene uncharacterized protein Neighboring gene trabuco

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. RUN domains: a new family of domains involved in Ras-like GTPase signaling. Callebaut I, et al. Trends Biochem Sci, 2001 Feb. PMID 11166556
    2. Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins. Gabernet-Castello C, et al. Mol Biol Cell, 2013 May. PMID 23485563, Free PMC Article
    3. A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses. Baranski TJ, et al. PLoS Genet, 2018 Apr. PMID 29608557, Free PMC Article
    4. Evi5 promotes collective cell migration through its Rab-GAP activity. Laflamme C, et al. J Cell Biol, 2012 Jul 9. PMID 22778279, Free PMC Article
    5. Identification of Cellular Genes Involved in Baculovirus GP64 Trafficking to the Plasma Membrane. Hodgson JJ, et al. J Virol, 2022 Jun 22. PMID 35608346, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG1695-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20433950..20445599
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167705.3 → NP_728346.2  uncharacterized protein Dmel_CG1695 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728346.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQ31
      Conserved Domains (4) summary
      smart00164
      Location:947 → 1124
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cd15784
      Location:310 → 485
      PH_RUTBC; Rab-binding Pleckstrin homology domain (PH) of small G-protein signaling modulator 1 and similar proteins
      pfam02759
      Location:63 → 237
      RUN; RUN domain
      cl22422
      Location:648 → 713
      SRP68-RBD; RNA-binding domain of signal recognition particle subunit 68
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQ31 Q8IQ31

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools