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    Cyp28d2 Cytochrome P450 28d2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp28d2provided by FlyBase
    Official Full Name
    Cytochrome P450 28d2provided by FlyBase
    Primary source
    FLYBASE:FBgn0031688
    Locus tag
    Dmel_CG6081
    See related
    AllianceGenome:FB:FBgn0031688
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    28d2; CG6081; Cyp28D2; CYP28D2; Dmel\CG6081
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in gonad. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp28d2 in Genome Data Viewer
    Location:
    25C10-25C10; 2-15 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5207267..5209345)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5207267..5209345)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Muscle-specific protein 300 kDa Neighboring gene ncRNA Neighboring gene small non-coding RNA 158 Neighboring gene Cytochrome P450 28d1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Naturally Segregating Variation at Ugt86Dd Contributes to Nicotine Resistance in Drosophila melanogaster. Highfill CA, et al. Genetics, 2017 Sep. PMID 28743761, Free PMC Article
    2. The Drosophila KASH domain proteins Msp-300 and Klarsicht and the SUN domain protein Klaroid have no essential function during oogenesis. Technau M, et al. Fly (Austin), 2008 Mar-Apr. PMID 18820478
    3. Detecting highly differentiated copy-number variants from pooled population sequencing. Schrider DR, et al. Pac Symp Biocomput, 2013. PMID 23424139, Free PMC Article
    4. Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits. Chakraborty M, et al. Nat Commun, 2019 Oct 25. PMID 31653862, Free PMC Article
    5. Metabolic activation and toxicological evaluation of polychlorinated biphenyls in Drosophila melanogaster. Idda T, et al. Sci Rep, 2020 Dec 9. PMID 33299007, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 28d2
    Names
    CG6081-PA
    Cyp28d2-PA
    cytochrome P450
    NP_608911.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5207267..5209345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135067.3 → NP_608911.1  cytochrome P450 28d2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608911.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VMT6
      Related
      FBpp0078697
      Conserved Domains (1) summary
      cl12078
      Location:38 → 475
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMT6.1 Q9VMT6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
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