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    CG7231 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34086, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7231provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031968
    Locus tag
    Dmel_CG7231
    See related
    AllianceGenome:FB:FBgn0031968
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7231
    Summary
    Predicted to be active in extracellular space. Is expressed in adult head. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to several human genes including FAM151B (family with sequence similarity 151 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7231 in Genome Data Viewer
    Location:
    28D3-28D3; 2-29 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7983946..7986785)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7983946..7986785)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Serpin 28Da Neighboring gene Serpin 28Db Neighboring gene Sno oncogene Neighboring gene antisense RNA:CR44996 Neighboring gene peste Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. Ghosh S, et al. Hum Mol Genet, 2004 Sep 15. PMID 15254017
    2. [LTR retrotransposons as a source of promoters in the Drosophila genome]. Makunin IV, et al. Genetika, 2010 Sep. PMID 21061618
    3. Drosophila SnoN modulates growth and patterning by antagonizing TGF-beta signalling. Ramel MC, et al. Mech Dev, 2007 Apr. PMID 17289352
    4. dSno facilitates baboon signaling in the Drosophila brain by switching the affinity of Medea away from Mad and toward dSmad2. Takaesu NT, et al. Genetics, 2006 Nov. PMID 16951053, Free PMC Article
    5. Characterization of dSnoN and its relationship to Decapentaplegic signaling in Drosophila. Barrio R, et al. Dev Biol, 2007 Jun 1. PMID 17434471

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7231-PC
    CG7231-PD
    CG7231-PE
    CG7231-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7983946..7986785
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164776.4 → NP_723327.1  uncharacterized protein Dmel_CG7231, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723327.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G7H7Z7, Q9VLU9
      Related
      FBpp0289422
      Conserved Domains (1) summary
      pfam10223
      Location:63 → 319
      DUF2181; Uncharacterized conserved protein (DUF2181)

    2. NM_135323.5 → NP_609167.3  uncharacterized protein Dmel_CG7231, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609167.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      G7H7Z7, Q8IPH1, Q8MQP2
      Conserved Domains (1) summary
      pfam10223
      Location:8 → 261
      DUF2181; Uncharacterized conserved protein (DUF2181)

    3. NM_001259004.1 → NP_001245933.1  uncharacterized protein Dmel_CG7231, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245933.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G7H7Z7, Q8IPH1, Q8MQP2
      Conserved Domains (1) summary
      pfam10223
      Location:8 → 261
      DUF2181; Uncharacterized conserved protein (DUF2181)

    4. NM_205923.3 → NP_995645.1  uncharacterized protein Dmel_CG7231, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995645.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G7H7Z7, Q8IPH1, Q8MQP2
      Conserved Domains (1) summary
      pfam10223
      Location:8 → 261
      DUF2181; Uncharacterized conserved protein (DUF2181)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MQP2 Q8MQP2
    Q9VLU9 Q9VLU9

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