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    mtsh mitoshell [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34141, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mtshprovided by FlyBase
    Official Full Name
    mitoshellprovided by FlyBase
    Primary source
    FLYBASE:FBgn0262598
    Locus tag
    Dmel_CG7795
    See related
    AllianceGenome:FB:FBgn0262598
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7795; Dmel\CG7795
    Summary
    Involved in spermatogenesis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mtsh in Genome Data Viewer
    Location:
    29A4-29A4; 2-31 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8316889..8319908, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8316889..8319908, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Oligosaccharide transferase gamma subunit Neighboring gene Methyltransferase like 14 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene stratum Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel predicted bromodomain-related protein affects coordination between meiosis and spermiogenesis in Drosophila and is required for male meiotic cytokinesis. Bergner LM, et al. DNA Cell Biol, 2010 Sep. PMID 20491580, Free PMC Article
    2. The SUMO Ligase Su(var)2-10 Controls Hetero- and Euchromatic Gene Expression via Establishing H3K9 Trimethylation and Negative Feedback Regulation. Ninova M, et al. Mol Cell, 2020 Feb 6. PMID 31901448, Free PMC Article
    3. Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster. Vedelek V, et al. Int J Mol Sci, 2024 Apr 3. PMID 38612789, Free PMC Article
    4. Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila. Janic A, et al. Science, 2010 Dec 24. PMID 21205669
    5. Cytokinesis in Drosophila male meiosis. Giansanti MG, et al. Spermatogenesis, 2012 Jul 1. PMID 23094234, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. molecular cloning of the mitoshell gene (CG7795); it encodes a novel protein with a bromodomain-related region; speculate that Mitoshell may participate in transcriptional regulation of spermatogenesis-specific genes
      Title: A novel predicted bromodomain-related protein affects coordination between meiosis and spermiogenesis in Drosophila and is required for male meiotic cytokinesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitoshell
    Names
    CG7795-PC
    CG7795-PD
    mtsh-PC
    mtsh-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8316889..8319908 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135364.3 → NP_609208.2  mitoshell, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609208.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VLP4

    2. NM_164806.3 → NP_723373.2  mitoshell, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723373.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPF9, Q8MSA8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSA8 Q8MSA8
    Q9VLP4.2 Q9VLP4

    Gene LinkOut

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