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    CG44153 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34341, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG44153provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0265002
    Locus tag
    Dmel_CG44153
    See related
    AllianceGenome:FB:FBgn0265002
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BP1029; CG13132; CG13134; CG13136; CG31714; CG34048; CG42843; CG5833; Dmel\CG44153
    Old locus tag
    Dmel_CG13134; Dmel_CG13136; Dmel_CG31714; Dmel_CG34048; Dmel_CG42843
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG44153 in Genome Data Viewer
    Location:
    31A2-31B1; 2-39 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10064121..10180256, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10064121..10180256, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Serpin 31A Neighboring gene Pendulin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Sulfonylurea receptor Neighboring gene Fumarase 4 Neighboring gene RPA-interacting protein alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide association in Drosophila identifies a role for Piezo and Proc-R in sleep latency. Eiman MN, et al. Sci Rep, 2024 Jan 2. PMID 38168575, Free PMC Article
    2. Genetic variation in the shape of cold-survival curves in a single fly population suggests potential for selection from climate variability. Teets NM, et al. J Evol Biol, 2018 Apr. PMID 29345010
    3. Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster. Highfill CA, et al. PLoS Genet, 2019 May. PMID 31107875, Free PMC Article
    4. Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi. Housden BE, et al. Sci Signal, 2015 Sep 8. PMID 26350902, Free PMC Article
    5. GWAS reveal a role for the central nervous system in regulating weight and weight change in response to exercise. Watanabe LP, et al. Sci Rep, 2021 Mar 4. PMID 33664357, Free PMC Article

    See all (50) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    mobile_element

    • Loc: c10118565-10118445 mobile_element_type = transposon:H{}6189
    • Loc: c10143384-10138214 mobile_element_type = transposon:Rt1b{}334
    • Loc: c10163789-10156377 mobile_element_type = transposon:blood{}335

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG44153-PA
    CG44153-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10064121..10180256 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273385.1 → NP_001260314.1  uncharacterized protein Dmel_CG44153, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260314.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL42
      Conserved Domains (5) summary
      cd00096
      Location:474 → 551
      Ig; Immunoglobulin domain
      smart00410
      Location:564 → 653
      IG_like; Immunoglobulin like
      cd00054
      Location:264 → 294
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam02793
      Location:661 → 718
      HRM; Hormone receptor domain
      cl11960
      Location:572 → 642
      Ig; Immunoglobulin domain

    2. NM_001103666.3 → NP_001097136.2  uncharacterized protein Dmel_CG44153, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097136.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL42
      Conserved Domains (5) summary
      cd00096
      Location:474 → 551
      Ig; Immunoglobulin domain
      smart00410
      Location:564 → 653
      IG_like; Immunoglobulin like
      cd00054
      Location:264 → 294
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam02793
      Location:661 → 718
      HRM; Hormone receptor domain
      cl11960
      Location:572 → 642
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MR60 Q8MR60
    Q9VL42 Q9VL42

    Gene LinkOut

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