U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG31760 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34642, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG31760provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051760
    Locus tag
    Dmel_CG31760
    See related
    AllianceGenome:FB:FBgn0051760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE52162; CG17214; CG17215; Dmel\CG31760
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1E. Orthologous to human GPR158 (G protein-coupled receptor 158) and GPR179 (G protein-coupled receptor 179). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG31760 in Genome Data Viewer
    Location:
    33D2-33D2; 2-46 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12142780..12170508)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12142780..12170508)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene rhomboid-6 Neighboring gene Gustatory receptor 33a Neighboring gene uncharacterized protein Neighboring gene Zinc transporter 33D Neighboring gene long non-coding RNA:CR43356 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene crooked

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Belly roll, a GPI-anchored Ly6 protein, regulates Drosophila melanogaster escape behaviors by modulating the excitability of nociceptive peptidergic interneurons. Li K, et al. Elife, 2023 Jun 13. PMID 37309249, Free PMC Article
    2. Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors. Metpally RP, et al. BMC Genomics, 2005 Aug 10. PMID 16091152, Free PMC Article
    3. Drosophila melanogaster G protein-coupled receptors. Brody T, et al. J Cell Biol, 2000 Jul 24. PMID 10908591, Free PMC Article
    4. Dopamine and GPCR-mediated modulation of DN1 clock neurons gates the circadian timing of sleep. Schlichting M, et al. Proc Natl Acad Sci U S A, 2022 Aug 23. PMID 35969763, Free PMC Article
    5. Outside-in signaling--a brief review of GPCR signaling with a focus on the Drosophila GPCR family. Hanlon CD, et al. J Cell Sci, 2015 Oct 1. PMID 26345366, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG31760-PB
    CG31760-PC
    CG31760-PD

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      12142780..12170508
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164996.3 → NP_723730.2  uncharacterized protein Dmel_CG31760, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723730.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      E1JHG5, Q8MT43, Q9VKA4
      Conserved Domains (2) summary
      smart00261
      Location:486 → 508
      FU; Furin-like repeats
      pfam00003
      Location:526 → 754
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR

    2. NM_001169491.2 → NP_001162962.1  uncharacterized protein Dmel_CG31760, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162962.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VKA4
      Conserved Domains (2) summary
      smart00261
      Location:486 → 508
      FU; Furin-like repeats
      pfam00003
      Location:526 → 754
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR

    3. NM_001273473.2 → NP_001260402.1  uncharacterized protein Dmel_CG31760, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260402.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VKA4
      Conserved Domains (2) summary
      smart00261
      Location:486 → 508
      FU; Furin-like repeats
      pfam00003
      Location:526 → 754
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKA4.3 Q9VKA4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools