Vamp7 Vesicle-associated membrane protein 7 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Vamp7provided by FlyBase
Official Full Name: Vesicle-associated membrane protein 7provided by FlyBase
Primary source: FLYBASE:FBgn0266186
Locus tag: Dmel_CG1599
See related: AllianceGenome:FB:FBgn0266186
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG1599; Dmel\CG1599; dVamp7; Ti-VAMP; TI-VAMP; vamp7; VAMP7; VAMP7/8; Vamp8; VAMP8
Summary: Enables SNAP receptor activity and SNARE binding activity. Involved in T-tubule organization; autophagosome maturation; and secretory granule-lysosome fusion. Located in autolysosome. Part of SNARE complex. Is expressed in adult head; adult heart; and organism. Orthologous to human VAMP7 (vesicle associated membrane protein 7). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (9841080..9842502, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (5728585..5730007, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables SNAP receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables SNAP receptor activity	IC Inferred by Curator more info	PubMed
enables SNAP receptor activity	IPI Inferred from Physical Interaction more info	PubMed
enables SNARE binding	IBA Inferred from Biological aspect of Ancestor more info
enables SNARE binding	IPI Inferred from Physical Interaction more info	PubMed
enables syntaxin binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in T-tubule organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in autophagosome maturation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in endosome to lysosome transport	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in secretory granule-lysosome fusion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vesicle fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle fusion	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of SNARE complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SNARE complex	IDA Inferred from Direct Assay more info	PubMed
part_of SNARE complex	IPI Inferred from Physical Interaction more info	PubMed
part_of SNARE complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in autolysosome	IDA Inferred from Direct Assay more info	PubMed
located_in late endosome membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info

Names: CG1599-PA; CG1599-PC; Vamp7-PA; Vamp7-PC; vesicle-associated membrane protein 7

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