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    BomS1 Bomanin Short 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37100, updated on 9-Dec-2024

    Summary

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    Official Symbol
    BomS1provided by FlyBase
    Official Full Name
    Bomanin Short 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0034329
    Locus tag
    Dmel_CG18108
    See related
    AllianceGenome:FB:FBgn0034329
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH08745; Bom1; CG18108; DIM 1; DIM-1; DIM1; Dmel\CG18108; IM-1; IM1; IM2-like
    Summary
    Involved in antifungal humoral response and response to mycotoxin. Located in extracellular region. Is expressed in embryonic midgut chamber. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See BomS1 in Genome Data Viewer
    Location:
    55C4-55C4; 2-85 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18383949..18384378)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14271454..14271883)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Bomanin Tailed 1 Neighboring gene Bomanin Bicipital 1 Neighboring gene Bomanin Short 4 Neighboring gene Bomanin Bicipital 2 Neighboring gene Bomanin Short 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Infection-derived lipids elicit an immune deficiency circuit in arthropods. Shaw DK, et al. Nat Commun, 2017 Feb 14. PMID 28195158, Free PMC Article
    2. Microbiome assembly on Drosophila body surfaces benefits the flies to combat fungal infections. Hong S, et al. iScience, 2022 Jun 17. PMID 35663020, Free PMC Article
    3. Activation of immune defences against parasitoid wasps does not underlie the cost of infection. Leitão AB, et al. Front Immunol, 2023. PMID 38130722, Free PMC Article
    4. The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster. Smith BR, et al. PLoS Pathog, 2023 Aug. PMID 37549163, Free PMC Article
    5. Inhibition of NF-κB in astrocytes is sufficient to delay neurodegeneration induced by proteotoxicity in neurons. Li YX, et al. J Neuroinflammation, 2018 Sep 11. PMID 30205834, Free PMC Article

    See all (124) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in antifungal humoral response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in defense response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to bacterium HEP PubMed 
    involved_in response to mycotoxin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bomanin short 1
    Names
    BomS1-PA
    CG18108-PA
    Immune-induced peptide 1 precursor
    bomanin 1
    bomanin S1
    immune induced molecule 1
    immune-induced molecule 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18383949..18384378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137475.3 → NP_611319.1  bomanin short 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611319.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P82706, Q9V8F6
      Related
      FBpp0085843
      Conserved Domains (1) summary
      pfam08194
      Location:1 → 40
      DIM; DIM protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P82706.2 P82706
    Q8MZG7 Q8MZG7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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