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    CG4250 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37599, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4250provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034761
    Locus tag
    Dmel_CG4250
    See related
    AllianceGenome:FB:FBgn0034761
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH52355; CT13934; Dmel\CG4250
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be located in cytoplasmic side of endosome membrane. Is expressed in wing hinge primordium and wing pouch. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4250 in Genome Data Viewer
    Location:
    58F4-58F4; 2-100 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22663692..22664474)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18551197..18551979)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45269 Neighboring gene long non-coding RNA:CR42868 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes. Stevaux O, et al. Cell Cycle, 2005 Sep. PMID 16082225
    2. Genomic changes under rapid evolution: selection for parasitoid resistance. Jalvingh KM, et al. Proc Biol Sci, 2014 Mar 22. PMID 24500162, Free PMC Article
    3. Genome-wide transcriptional analysis of Drosophila larvae infected by entomopathogenic nematodes shows involvement of complement, recognition and extracellular matrix proteins. Arefin B, et al. J Innate Immun, 2014. PMID 23988573, Free PMC Article
    4. During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay. Katsuyama T, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25902518, Free PMC Article
    5. Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila. Kuuluvainen E, et al. J Biol Chem, 2014 Jun 6. PMID 24778181, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic side of endosome membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4250-PA
    CG4250-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22663692..22664474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259539.2 → NP_001246468.1  uncharacterized protein Dmel_CG4250, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246468.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K8A8
      Conserved Domains (1) summary
      pfam10601
      Location:66 → 133
      zf-LITAF-like; LITAF-like zinc ribbon domain

    2. NM_137859.4 → NP_611703.1  uncharacterized protein Dmel_CG4250, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611703.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W218
      Related
      FBpp0071776
      Conserved Domains (1) summary
      pfam10601
      Location:53 → 120
      zf-LITAF-like; LITAF-like zinc ribbon domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K8A8 A0A0B4K8A8
    Q9W218 Q9W218

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