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    CG30183 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37749, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30183provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050183
    Locus tag
    Dmel_CG30183
    See related
    AllianceGenome:FB:FBgn0050183
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4093; CG4530; Dmel\CG30183
    Summary
    Predicted to enable actin binding activity. Predicted to be involved in actomyosin contractile ring assembly; mitotic cytokinesis; and septin ring organization. Predicted to be located in actin cytoskeleton and nucleoplasm. Predicted to be active in actomyosin contractile ring. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30183 in Genome Data Viewer
    Location:
    59F6-59F6; 2-104 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23690247..23697824, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19577770..19585347, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Sulfotransferase 1 Neighboring gene Sulfotransferase 3 Neighboring gene lethal (2) essential for life Neighboring gene Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2 Neighboring gene angel Neighboring gene mitochondrial ribosomal protein L43 Neighboring gene salivary glands marred Neighboring gene lethal-(2)-denticleless

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Animal Cell Cytokinesis: The Rho-Dependent Actomyosin-Anilloseptin Contractile Ring as a Membrane Microdomain Gathering, Compressing, and Sorting Machine. Carim SC, et al. Front Cell Dev Biol, 2020. PMID 33117802, Free PMC Article
    2. Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects. Temme C, et al. Front Genet, 2014. PMID 24904643, Free PMC Article
    3. A cell atlas of the adult Drosophila midgut. Hung RJ, et al. Proc Natl Acad Sci U S A, 2020 Jan 21. PMID 31915294, Free PMC Article
    4. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article
    5. Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. Lowe N, et al. Development, 2014 Oct. PMID 25294943, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in actomyosin contractile ring assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic cytokinesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in septin ring organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in actin cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in actomyosin contractile ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30183-PA
    CG30183-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23690247..23697824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144273.2 → NP_001137745.2  uncharacterized protein Dmel_CG30183, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137745.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7YZP5, Q86NU0, Q9W1L2
      Conserved Domains (2) summary
      cd01263
      Location:1438 → 1549
      PH_anillin; Anillin Pleckstrin homology (PH) domain
      pfam00169
      Location:1442 → 1546
      PH; PH domain

    2. NM_137975.3 → NP_611819.2  uncharacterized protein Dmel_CG30183, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611819.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7YZP5, Q86NU0, Q9W1L2
      Conserved Domains (2) summary
      cd01263
      Location:1438 → 1549
      PH_anillin; Anillin Pleckstrin homology (PH) domain
      pfam00169
      Location:1442 → 1546
      PH; PH domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86NU0 Q86NU0
    Q9W1L2 Q9W1L2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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