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    CG3448 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39094, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3448provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035996
    Locus tag
    Dmel_CG3448
    See related
    AllianceGenome:FB:FBgn0035996
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3448
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in DNA ligation involved in DNA repair; double-strand break repair via nonhomologous end joining; and response to X-ray. Predicted to be located in nucleus. Predicted to be part of DNA ligase IV complex and DNA-dependent protein kinase-DNA ligase 4 complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3448 in Genome Data Viewer
    Location:
    67B7-67B7; 3-29 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9450545..9451572, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9443645..9444672, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Blocked early in transport 3 Neighboring gene Nuclear factor Y-box A Neighboring gene Sting-regulated gene 3 Neighboring gene uncharacterized protein Neighboring gene ghiberti Neighboring gene pleiohomeotic like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila pho-like gene encodes a YY1-related DNA binding protein that is redundant with pleiohomeotic in homeotic gene silencing. Brown JL, et al. Development, 2003 Jan. PMID 12466196
    2. E2 ligase dRad6 regulates DMP53 turnover in Drosophila. Chen S, et al. J Biol Chem, 2011 Mar 18. PMID 21205821, Free PMC Article
    3. Myopathic lamin mutations cause reductive stress and activate the nrf2/keap-1 pathway. Dialynas G, et al. PLoS Genet, 2015 May. PMID 25996830, Free PMC Article
    4. DNA Repair in Drosophila: Mutagens, Models, and Missing Genes. Sekelsky J. Genetics, 2017 Feb. PMID 28154196, Free PMC Article
    5. Blue light induces a neuroprotective gene expression program in Drosophila photoreceptors. Hall H, et al. BMC Neurosci, 2018 Jul 20. PMID 30029619, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA ligation involved in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in double-strand break repair via nonhomologous end joining IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to X-ray IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of DNA ligase IV complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of DNA-dependent protein kinase-DNA ligase 4 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3448-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9450545..9451572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140059.3 → NP_648316.1  uncharacterized protein Dmel_CG3448 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648316.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSZ2
      Related
      FBpp0076204
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VSZ2 Q9VSZ2

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